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严重骨质疏松作为遗传性血色素沉着症的非典型表现。

Severe osteoporosis as atypical presentation of hereditary hemochromatosis.

作者信息

Taujan Georgiana Cristina, Iconaru Laura, Rosu Mihaela, Kosmopoulou Olga Ana, Papadopoulou Ioana Blerta, Baleanu Felicia

机构信息

Department of Endocrinology Centre Hospitalier Universitaire Brugmann Brussels Belgium.

出版信息

Clin Case Rep. 2022 Oct 8;10(10):e6396. doi: 10.1002/ccr3.6396. eCollection 2022 Oct.

Abstract

Besides important metabolic repercussions, iron overload is reported to be associated with deleterious effects on articulations and bones. We present the case of a male patient diagnosed with severe osteoporosis and vertebral fracture, in whom the evaluation for secondary osteoporosis revealed hereditary hemochromatosis.

摘要

除了重要的代谢影响外,据报道铁过载与关节和骨骼的有害影响有关。我们报告了一例被诊断为严重骨质疏松症和椎体骨折的男性患者,对其继发性骨质疏松症的评估显示为遗传性血色素沉着症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7bd/9547343/7364365bd137/CCR3-10-e6396-g005.jpg

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本文引用的文献

1
Secondary Osteoporosis.
Endocr Rev. 2022 Mar 9;43(2):240-313. doi: 10.1210/endrev/bnab028.
3
Impaired Bone Microarchitecture in Patients with Hereditary Hemochromatosis and Skeletal Complications.
Calcif Tissue Int. 2020 May;106(5):465-475. doi: 10.1007/s00223-020-00658-7. Epub 2020 Jan 27.
4
Diagnosis and Treatment of Genetic -Hemochromatosis: The Danish Aspect.
Gastroenterology Res. 2019 Oct;12(5):221-232. doi: 10.14740/gr1206. Epub 2019 Oct 4.
6
Clinical Impact and Cellular Mechanisms of Iron Overload-Associated Bone Loss.
Front Pharmacol. 2017 Feb 21;8:77. doi: 10.3389/fphar.2017.00077. eCollection 2017.
7
Effect of C282Y genotype on self-reported musculoskeletal complications in hereditary hemochromatosis.
PLoS One. 2015 Mar 30;10(3):e0122817. doi: 10.1371/journal.pone.0122817. eCollection 2015.
8
Bone loss caused by iron overload in a murine model: importance of oxidative stress.
Blood. 2010 Oct 7;116(14):2582-9. doi: 10.1182/blood-2009-12-260083. Epub 2010 Jun 16.
9
Association between iron overload and osteoporosis in patients with hereditary hemochromatosis.
Osteoporos Int. 2009 Apr;20(4):549-55. doi: 10.1007/s00198-008-0701-4. Epub 2008 Jul 26.
10
Bone mineral density in men with genetic hemochromatosis and HFE gene mutation.
Osteoporos Int. 2005 Dec;16(12):1809-14. doi: 10.1007/s00198-005-1934-0. Epub 2005 Jun 1.

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