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荧光素引导下的硬脊膜内脊髓肿瘤手术:单中心经验

Fluorescein-guided surgery for intradural spinal tumors: A single-center experience.

作者信息

Cardali Salvatore Massimiliano, Ricciardo Giuseppe, Garufi Giada, Raffa Giovanni, Messineo Francesco, Scalia Gianluca, Conti Alfredo, Germanò Antonino

机构信息

Division of Neurosurgery, BIOMORF Department, University of Messina, Messina, Italy.

Neurosurgery Unit, Papardo Hospital, Messina, Italy.

出版信息

Brain Spine. 2022 Jun 22;2:100908. doi: 10.1016/j.bas.2022.100908. eCollection 2022.

DOI:10.1016/j.bas.2022.100908
PMID:36248155
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9560644/
Abstract

•Gross total removal has a pivotal role in surgical treatment of intradural spinal tumors.•Sodium fluorescein prevents vascular injuries also preserving pial vessels in posterior myelotomy.•Fluorescence before the durotomy helps to distinguishing tumor from healthy tissue in intradural lesions.•Intraoperative fluorescence is safe and effective, also preserving functional anatomy in tumor removal.

摘要

•全切除在硬脊膜内脊髓肿瘤的外科治疗中起着关键作用。

•荧光素钠可预防血管损伤,同时在脊髓后正中切开术中保留软膜血管。

•硬脑膜切开前的荧光有助于在硬脊膜内病变中区分肿瘤与健康组织。

•术中荧光是安全有效的,在肿瘤切除过程中还能保留功能解剖结构。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d079/9560644/e71e2c283a76/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d079/9560644/dfa5cae29298/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d079/9560644/e71e2c283a76/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d079/9560644/dfa5cae29298/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d079/9560644/e71e2c283a76/gr2.jpg

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本文引用的文献

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Front Oncol. 2021 Jan 28;10:618579. doi: 10.3389/fonc.2020.618579. eCollection 2020.
2
An overview of the tumors affecting the spine-inside to out.从内到外影响脊柱的肿瘤概述。
Neurooncol Pract. 2020 Nov 18;7(Suppl 1):i10-i17. doi: 10.1093/nop/npaa049. eCollection 2020 Nov.
3
Fluorescein-guided surgery for spinal gliomas: Analysis of 220 consecutive cases.荧光素引导下的脊柱胶质瘤手术:220 例连续病例分析。
Int Rev Neurobiol. 2020;151:139-154. doi: 10.1016/bs.irn.2020.03.004. Epub 2020 May 13.
4
Fluorescein Application in Cranial and Spinal Tumors Enhancing at Preoperative MRI and Operated With a Dedicated Filter on the Surgical Microscope: Preliminary Results in 279 Patients Enrolled in the FLUOCERTUM Prospective Study.荧光素在术前MRI增强的颅脑和脊髓肿瘤中的应用及在手术显微镜上使用专用滤光片进行手术:FLUOCERTUM前瞻性研究中279例患者的初步结果
Front Surg. 2019 Aug 13;6:49. doi: 10.3389/fsurg.2019.00049. eCollection 2019.
5
The role of 5-aminolevulinic acid in spinal tumor surgery: a review.5-氨基酮戊酸在脊柱肿瘤手术中的作用:综述。
J Neurooncol. 2019 Feb;141(3):575-584. doi: 10.1007/s11060-018-03080-0. Epub 2018 Dec 29.
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