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[胎儿自然死亡。产妇年龄、产次及既往流产史的作用]

[Spontaneous fetal mortality. Role of maternal age, parity and previous abortions].

作者信息

Leridon H

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1987;16(4):425-31.

PMID:3624817
Abstract

Analysing the reproductive biographies of samples of women has made it possible to clarify the role of various factors in bringing about a risk of spontaneous fetal death during the reproductive life of the mother. However, attention must be paid to the difficulties in observing the cases and measuring parameters. To make the various features comparable it is necessary to distinguish between apparent intra-uterine mortality (the pregnancy being diagnosed by the woman), recognisable (the pregnancy is diagnosable clinically) and total (from the time of fertilisation). The effect of maternal age is definite and quite independent of parity. Apparent intra-uterine mortality rises from about 120 per 1,000 pregnancies at the age of 20-24 to 200 per 1,000 at 35-39 and 270 per 1,000 at 40-44. If there has been no previous abortion the risks generally are less than 150 per 1,000, but if there has been even one previous abortion they become practically double. This discontinuity can be interpreted as showing the existence of marked changes between women as far as this risk is concerned.

摘要

对女性样本的生殖经历进行分析,有助于阐明各种因素在导致母亲生育期内胎儿自然死亡风险方面所起的作用。然而,必须注意观察病例和测量参数时存在的困难。为了使各种特征具有可比性,有必要区分明显的宫内死亡率(由女性诊断出怀孕)、可识别的(临床上可诊断出怀孕)和总的(从受精时起)。母亲年龄的影响是确定的,且与产次完全无关。明显的宫内死亡率从20 - 24岁时每1000例怀孕约120例,上升到35 - 39岁时每1000例200例,40 - 44岁时每1000例270例。如果之前没有流产,风险通常低于每1000例150例,但如果之前哪怕有过一次流产,风险实际上就会翻倍。这种不连续性可以解释为表明就这种风险而言,女性之间存在明显差异。

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