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侯赛因国王癌症中心的巴勒斯坦癌症患者。

Palestinian Patients with Cancer at King Hussein Cancer Center.

作者信息

Mansour Razan, Amarin Justin Z, Al-Ani Abdallah, Al-Hussaini Maysa, Mansour Asem

机构信息

Office of Scientific Affairs and Research, King Hussein Cancer Center, Amman, Jordan.

Department of Pathology and Laboratory Medicine, King Hussein Cancer Center, Amman, Jordan.

出版信息

Front Oncol. 2022 Sep 30;12:997492. doi: 10.3389/fonc.2022.997492. eCollection 2022.

Abstract

BACKGROUND

The Palestinian Ministry of Health (MoH) routinely refers Palestinian patients with cancer to King Hussein Cancer Center (KHCC), the largest cancer center in the Middle East.

AIMS

We aimed to describe the characteristics of Palestinian patients with cancer.

METHODS

We performed a retrospective chart review of all Palestinian patients with cancer who were treated at KHCC during 2018 and 2019, of which demographic and clinical characteristics were presented.

RESULTS

We initially started with 521 cases, out of which 41 (7.9%) cases were excluded due to misdiagnosis as malignant on pathology review. We included 480 patients with a confirmed diagnosed of cancer. Most patients were adults (88.8%) with a mean age of 50.0 ± 15.0 years ranging from 19 to 87 years. The most common cancer sites in adult men, who comprised 46.9% of the cohort were the hematolymphoid system (23.5%), followed by the digestive system (17.5%), and lung and pleura (11.5%). In women (53.1%), the most common cancer sites were the breast (46.0%), followed by the digestive system (15.0%), and the hematolymphoid system (10.2%). Children and adolescents accounted for 11.3% of the total cases, among which the hematolymphoid system was the most common cancer site (50%), followed by the brain (14.8%). About 36.0% of all patients presented with advanced-stage disease (i.e., distant metastasis).

CONCLUSION

The most common cancer sites in our cohort are generally similar to data from the Palestinian territories. Many patients presented with advanced-stage disease, which signals the need for awareness campaigns and screening programs. Benign tumors are misdiagnosed in many patients as cancer. The limited resources and facilities including human resources remain important challenges to the proper and timely diagnosis and management of cancer among Palestinians living in the Palestinian Territories.

摘要

背景

巴勒斯坦卫生部(MoH)通常会将患有癌症的巴勒斯坦患者转介至侯赛因国王癌症中心(KHCC),该中心是中东地区最大的癌症中心。

目的

我们旨在描述巴勒斯坦癌症患者的特征。

方法

我们对2018年至2019年期间在KHCC接受治疗的所有巴勒斯坦癌症患者进行了回顾性病历审查,并呈现了其人口统计学和临床特征。

结果

我们最初有521例病例,其中41例(7.9%)因病理检查误诊为恶性而被排除。我们纳入了480例确诊为癌症的患者。大多数患者为成年人(88.8%),平均年龄为50.0±15.0岁,年龄范围为19至87岁。占队列46.9%的成年男性中,最常见的癌症部位是血液淋巴系统(23.5%),其次是消化系统(17.5%)以及肺和胸膜(11.5%)。在女性(53.1%)中,最常见的癌症部位是乳腺(46.0%),其次是消化系统(15.0%)以及血液淋巴系统(10.2%)。儿童和青少年占总病例的11.3%,其中血液淋巴系统是最常见的癌症部位(50%),其次是脑(14.8%)。所有患者中约36.0%表现为晚期疾病(即远处转移)。

结论

我们队列中最常见的癌症部位总体上与巴勒斯坦领土的数据相似。许多患者表现为晚期疾病,这表明需要开展提高认识运动和筛查项目。许多患者的良性肿瘤被误诊为癌症。包括人力资源在内的有限资源和设施仍然是居住在巴勒斯坦领土的巴勒斯坦人进行癌症正确和及时诊断及管理的重要挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73c6/9561845/8b9624a91cee/fonc-12-997492-g001.jpg

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