Dias Antunes Joana, Almeida Patrícia, Barreiro Ivo, Gonçalves Abílio
Internal Medicine, Hospital Distrital da Figueira da Foz, Figueira da Foz, PRT.
Cureus. 2022 Sep 11;14(9):e29052. doi: 10.7759/cureus.29052. eCollection 2022 Sep.
Lymphomas result from the proliferation of malignant lymphocytes, which can affect lymph nodes, blood, and other organs. Primary involvement of the spine by haematological diseases is rare. Non-Hodgkin's lymphoma with an extranodal location most frequently involves the gastrointestinal tract and airways, affecting the bone, muscle, and nervous system. We present a clinical case of an atypical form of non-Hodgkin's lymphoma. A 78-year-old woman was admitted to the hospital with complaints of pain in the lumbar region, hip, and left leg for the last month. Computed tomography of the lumbar spine revealed a mass of left paravertebral tissue with involvement from L3 to L5. Thoraco-abdominal CT-guided biopsy revealed diffuse large-cell non-Hodgkin B lymphoma. The remainder of the study did not show lymphatic involvement, so a diagnosis of primary extranodal large cell non-Hodgkin B lymphoma was made.
淋巴瘤是由恶性淋巴细胞增殖引起的,可累及淋巴结、血液及其他器官。血液系统疾病原发性累及脊柱较为罕见。结外部位的非霍奇金淋巴瘤最常累及胃肠道和气道,也可累及骨骼、肌肉和神经系统。我们报告一例非典型非霍奇金淋巴瘤的临床病例。一名78岁女性因近一个月来腰部、髋部及左腿疼痛入院。腰椎计算机断层扫描显示左侧椎旁组织有肿块,累及L3至L5。胸腹部CT引导下活检显示弥漫性大细胞非霍奇金B淋巴瘤。其余检查未显示有淋巴受累,因此诊断为原发性结外大细胞非霍奇金B淋巴瘤。