Şanlıurfa Mehmet Akif İnan Training and Research Hospital, Department of Urology, Şanlıurfa, Turkey.
Karaman Training and Research Hospital, Department of Urology, Karaman, Turkey.
Andrology. 2023 Jan;11(1):10-16. doi: 10.1111/andr.13315. Epub 2022 Oct 25.
It has been understood that COVID-19, which has become a global pandemic in a short time, is a disease affecting multiple organs and systems. Some of the organs and systems affected by the disease also play a role in the pathophysiology of erectile dysfunction (ED), which led us to consider the possible effects of the disease on the erectile function. In this study, we aimed to evaluate changes in the erectile functions of patients with COVID-19 among those that had previously diagnosed with mild and moderate ED in our urology outpatient clinic.
Eighty-one patients aged 18-65 years who were confirmed to have COVID-19 were included in the study. According to disease severity, these patients were divided into two groups as mild (non-hospitalized, n = 60) and moderate (hospitalized but did not require intensive care, n = 21). The patients' pre- and post-disease scores in the five-item International Index of Erectile Function (IIEF-5) and hormone panel results were compared.
The changes in the IIEF-5 scores of the patients from the pre-disease to the post-disease period were statistically significant for both the mild and moderate groups (p < 0.05). When these changes were compared between the mild and moderate groups, the difference was not statistically significant (p = 0.156). There was also no statistically significant change in the testosterone, follicle-stimulating, luteinizing, and prolactin hormone levels before and after the disease.
In this study, we determined that SARS-CoV-2 infection caused deterioration in existing ED in sexually active male individuals, regardless of the severity of the disease.
众所周知,新冠病毒在短时间内迅速成为全球大流行疾病,它是一种影响多个器官和系统的疾病。该疾病影响的一些器官和系统也在勃起功能障碍(ED)的病理生理学中发挥作用,这促使我们考虑该疾病对勃起功能可能产生的影响。在本研究中,我们旨在评估我们泌尿科门诊中先前被诊断为轻度和中度 ED 的患者中 COVID-19 对勃起功能的影响。
共纳入 81 例年龄在 18-65 岁之间的 COVID-19 确诊患者。根据疾病严重程度,这些患者分为两组:轻症组(非住院,n=60)和中症组(住院但无需重症监护,n=21)。比较了患者在疾病前后的国际勃起功能指数(IIEF-5)的五分制评分和激素面板结果。
轻症和中症组患者的 IIEF-5 评分在疾病前后均有显著变化(p<0.05)。在轻症和中症组之间比较这些变化时,差异无统计学意义(p=0.156)。在疾病前后,睾酮、卵泡刺激素、黄体生成素和催乳素激素水平也没有统计学上的显著变化。
在本研究中,我们确定了 SARS-CoV-2 感染会使活跃男性患者的 ED 恶化,无论疾病的严重程度如何。