Dhillon Kunwardeep, Sankari Abdulghani
Detroit Medical Center/Wayne State University
Wayne State University
Idiopathic hypersomnia (IH) is a rare chronic sleep disorder introduced by Bedrich Roth in Prague in 1956. Idiopathic hypersomnia is characterized by excessive daytime sleepiness, uncontrollable need to sleep with long unrefreshing naps, and difficulty waking up from sleep in most instances despite average or longer amounts of nocturnal sleep for at least three months. Idiopathic hypersomnia is considered a disorder of neurological origin, classified as a central disorder of hypersomnolence; others include narcolepsy, type 1 and type 2, and Kleine-Levin syndrome. The condition's pathophysiology is poorly understood, making diagnosing and managing to challenge for clinicians. This article will review etiology, epidemiology, clinical manifestations, and the treatment of IH in adults.
特发性嗜睡症(IH)是一种罕见的慢性睡眠障碍,由贝德里希·罗斯于1956年在布拉格首次提出。特发性嗜睡症的特征是白天过度嗜睡、无法控制的睡眠需求以及长时间的无恢复感小睡,并且在大多数情况下,尽管夜间睡眠时间平均或更长,但仍难以从睡眠中醒来,这种情况至少持续三个月。特发性嗜睡症被认为是一种神经源性疾病,归类为中枢性过度嗜睡症;其他类型包括发作性睡病1型和2型以及克莱恩-莱文综合征。该病症的病理生理学尚不清楚,这给临床医生的诊断和治疗带来了挑战。本文将综述成人特发性嗜睡症的病因、流行病学、临床表现及治疗。