Department of Health and Behavior, Catholic University of Pelotas - Universidade Católica de Pelotas, Rua Gonçalves Chaves, 373, Sala 424C, 96015-560 Pelotas, RS, Brazil.
Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.
Encephale. 2023 Dec;49(6):572-576. doi: 10.1016/j.encep.2022.08.012. Epub 2022 Oct 15.
Anxiety disorders are among the most common psychiatric disorders in the general population. Our objective was to describe the cumulative incidence and risk factors of anxiety disorders, including obsessive-compulsive disorder (OCD) and posttraumatic stress disorder (PTSD), in a follow-up of young adults over a five-year period. This is a prospective cohort conducted in two waves. The first took place from 2007 to 2009, in which 1,560 young adults aged between 18 and 24 years were evaluated using the Mini-International Neuropsychiatric Interview (MINI). Subjects were invited to participate in the second wave, which wave took place from 2012 to 2014, where 1,244 young adults were evaluated using the MINI-Plus. Our findings showed a cumulative incidence of 10.9% for any anxiety disorder, 6.5% for generalized anxiety disorder, 6.0% for agoraphobia, 2.0% for OCD, 1.6% for panic disorder, 1.1% for social anxiety and 0.7% for PTSD. Being female and having had a depressive episode were risk factors to develop any anxiety disorder. We observed a high cumulative incidence of anxiety disorders in a population-based sample of young adults. Our data highlights the importance of the early identification of these disorders as this could lead to early illness detection, early illness management and a reduced burden of disease.
焦虑障碍是普通人群中最常见的精神障碍之一。我们的目的是描述在为期五年的随访中，年轻人中焦虑障碍（包括强迫症和创伤后应激障碍）的累积发病率和危险因素。这是一项在两个时间点进行的前瞻性队列研究。第一次在 2007 年至 2009 年进行，评估了 1560 名年龄在 18 至 24 岁之间的年轻人，使用的是 Mini-International Neuropsychiatric Interview（MINI）。邀请受试者参加第二次，即 2012 年至 2014 年的研究，其中评估了 1244 名年轻人，使用的是 MINI-Plus。我们的研究结果显示，任何焦虑障碍的累积发病率为 10.9%，广泛性焦虑障碍为 6.5%，广场恐怖症为 6.0%，强迫症为 2.0%，惊恐障碍为 1.6%，社交焦虑症为 1.1%，创伤后应激障碍为 0.7%。女性和经历过抑郁发作是发生任何焦虑障碍的危险因素。我们在一个基于人群的年轻成年人样本中观察到焦虑障碍的高累积发病率。我们的数据强调了早期识别这些障碍的重要性，因为这可能导致早期发现疾病、早期管理疾病和减轻疾病负担。
