Life and Health Department, University of Medicine and Pharmacy Mohammed V, Rabat, Morocco.
National Institute of Oncology, Rabat, Morocco.
J Evid Based Integr Med. 2022 Jan-Dec;27:2515690X221128036. doi: 10.1177/2515690X221128036.
Variety of conventional treatments are used to treat cancer. Cancer patients adopt other alternative therapies including medicinal plants. Their curative power results in the presence of secondary metabolites in its different parts. However, they can have toxic effects and interactions with conventional treatment and even chemosensitivity of the cancer cells.
This study aims to determine the prevalence of the use of medecinal plants by cancer patients undergoing chemotherapy, list the medecinal plants used, identify the most consumed, present the reported adverse effects and determine the predictive factors of their use.
This was a cross-sectional study of 203 patients followed at the National Institute of Oncology in Rabat from 01 October 2018 to 30 November 2018. Regarding socio-demographic and clinical characteristics and data on the use of medicinal plants were collected from a questionnaire.
of 203 patients, 37% used medicinal plants. 30 plants also the honey were identified during this study. The "euphorbia honey"was consumed at (40%), The most used plants were garlic (13%), turmeric, fenugreek and thyme (11% each). 5% of patients presented side effects related to the consumption of medicinal plants. There is a significant association between the use of medicinal plants and socio-economic level (p = 0.004) and duration of illness (p = 0.048).
This study revealed a high prevalence of medicinal plants used by cancer patients receiving chemotherapy at National Institute of Oncology. The more clinical studies are desirable to demonstrate the efficacy of medicinal plants and their therapeutic effects to encourage their consumption or prohibit them.
有多种常规疗法用于治疗癌症。癌症患者采用其他替代疗法,包括药用植物。其治疗效果源于其不同部位存在的次生代谢产物。然而,它们可能具有毒性作用,并与常规治疗产生相互作用,甚至影响癌细胞的化疗敏感性。
本研究旨在确定接受化疗的癌症患者使用药用植物的流行情况,列出使用的药用植物,确定最常使用的植物,报告报告的不良反应,并确定其使用的预测因素。
这是一项在 2018 年 10 月 1 日至 11 月 30 日期间在拉巴特国家肿瘤学研究所接受随访的 203 例患者的横断面研究。从问卷中收集社会人口学和临床特征以及药用植物使用数据。
在 203 例患者中,有 37%使用了药用植物。在这项研究中还确定了 30 种植物和蜂蜜。(40%)消费了“乳香蜂蜜”,最常使用的植物是大蒜(13%)、姜黄、葫芦巴和百里香(各 11%)。有 5%的患者出现与药用植物消费相关的不良反应。药用植物的使用与社会经济水平(p = 0.004)和疾病持续时间(p = 0.048)之间存在显著关联。
本研究揭示了在国家肿瘤学研究所接受化疗的癌症患者中使用药用植物的高流行率。需要进行更多的临床研究来证明药用植物的疗效及其治疗效果,以鼓励使用或禁止使用。