中性粒细胞-淋巴细胞比值和单核细胞-淋巴细胞比值与复杂肺部疾病的放射学严重程度的关系。
Neutrophil-Lymphocyte Ratio and Monocyte-Lymphocyte Ratio According to the Radiologic Severity of Complex Pulmonary Disease.
机构信息
Department of Internal Medicine, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea.
Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
出版信息
J Korean Med Sci. 2022 Oct 17;37(40):e292. doi: 10.3346/jkms.2022.37.e292.
BACKGROUND
To date, no study has investigated whether the neutrophil-lymphocyte ratio (NLR) and monocyte-lymphocyte ratio (MLR) have a clinical value in Mycobacterium avium complex (MAC)-pulmonary disease (PD).
METHODS
We aimed to assess whether the baseline NLR and MLR were different according to the severity of MAC-PD based on the radiologic classification by retrospectively analyzing 549 patients treated in a tertiary referral center in South Korea.
RESULTS
Both NLR and MLR were significantly higher as 3.33 and 0.43 respectively in the fibrocavitary type, followed by 2.34 and 0.27 in the cavitary nodular bronchiectatic type and significantly lower as 1.88 and 0.23 in the non-cavitary nodular bronchiectatic type.
CONCLUSION
The baseline NLR and MLR showed a distinct difference in accordance with the radiologic severity of MAC-PD.
背景
迄今为止，尚无研究探讨中性粒细胞与淋巴细胞比值（NLR）和单核细胞与淋巴细胞比值（MLR）在鸟分枝杆菌复合群（MAC）-肺部疾病（PD）中的临床价值。
方法
我们旨在通过回顾性分析韩国一家三级转诊中心的 549 名患者，评估基于影像学分类的 MAC-PD 严重程度时 NLR 和 MLR 的基线值是否存在差异。
结果
纤维空洞型 NLR 和 MLR 分别显著更高，分别为 3.33 和 0.43，空洞性结节性支气管扩张型分别为 2.34 和 0.27，非空洞性结节性支气管扩张型则显著更低，分别为 1.88 和 0.23。
结论
NLR 和 MLR 的基线值与 MAC-PD 的影像学严重程度存在明显差异。
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