一名IgA和C4缺乏患者出现硬皮病和溶血性贫血：一种迄今未被描述的关联。
Scleroderma and hemolytic anemia in a patient with deficiency of IgA and C4: a hitherto undescribed association.
作者信息
Jones E, Jones J V, Woodbury J F, Carr R I, Skanes V
出版信息
J Rheumatol. 1987 Jun;14(3):609-12.
PMID:3625644
Abstract
We describe a 66-year-old women with CREST variant of scleroderma who developed autoimmune hemolytic anemia responsive to prednisone and demonstrated a deficiency of IgA and the C4 component of complement. This association of clinical, immunologic and genetic findings has not previously been reported. The literature relating to these findings is reviewed and possible mechanisms are discussed.
摘要
我们描述了一位66岁患有硬皮病CREST变异型的女性，她出现了对泼尼松有反应的自身免疫性溶血性贫血，并表现出IgA和补体C4成分缺乏。这种临床、免疫和遗传发现的关联此前尚未有报道。本文回顾了与这些发现相关的文献并讨论了可能的机制。
相似文献
1
2
3
IgA deficiency and autoimmune hemolytic disease.IgA缺乏症与自身免疫性溶血性疾病。
Arch Intern Med. 1976 Jan;136(1):93-4.
4
[Autoimmune hemolytic anemia in a boy with IgA deficiency].[一名患有IgA缺乏症男孩的自身免疫性溶血性贫血]
Pediatr Pol. 1978 Apr;53(4):537-40.
5
Selective IgA deficiency with multiple autoimmune disorders.伴有多种自身免疫性疾病的选择性IgA缺乏症。
J Clin Lab Immunol. 1981 Jul;6(1):81-5.
6
[Porphyria cutanea tarda, scleroderma, leukopenia and hemolytic anemia. Clinical, biochemical and pathologic anatomical analysis of an uncommon syndrome].迟发性皮肤卟啉症、硬皮病、白细胞减少症和溶血性贫血。一种罕见综合征的临床、生化及病理解剖分析
Schweiz Med Wochenschr. 1967 Apr 29;97(17):538-46.
7
[Scleroderma and autoimmune hemolytic anemia. Case report].
Sem Hop. 1976;52(31-32):1709-13.
8
Progressive systemic scleroderma with iga deficiency in a child.一名儿童患进行性系统性硬化症伴IgA缺乏症。
Am J Dis Child. 1981 Oct;135(10):965-6. doi: 10.1001/archpedi.1981.02130340069021.
9
Pyoderma gangrenosum in a patient with autoimmune haemolytic anaemia and complement deficiency.
Br J Dermatol. 2000 Jul;143(1):154-6. doi: 10.1046/j.1365-2133.2000.03606.x.
10
Chronic mucocutaneous candidiasis, pernicious anaemia and IgA deficiency.慢性黏膜皮肤念珠菌病、恶性贫血和IgA缺乏症。
Br J Dermatol. 1979 Jul;101 Suppl 17:75.
引用本文的文献
1
Infectious diseases associated with complement deficiencies.与补体缺陷相关的传染病。
Clin Microbiol Rev. 1991 Jul;4(3):359-95. doi: 10.1128/CMR.4.3.359.
Zotero 插件