Augustine Matthew Robert, Thompson Scott, Powell Garret, Knavel-Koepsel Erica, Adamo Daniel, Bendel Emily, Anderson Katelyn, Bjarnason Haraldur, Tollefson Megha, Woodrum David A
Department of Radiology, Mayo Clinic, Rochester, Minnesota.
Department of Radiology, University of Wisconsin-Madison, Madison, Wisconsin.
J Vasc Interv Radiol. 2023 Feb;34(2):197-204. doi: 10.1016/j.jvir.2022.10.019. Epub 2022 Oct 17.
To evaluate the safety and effectiveness of percutaneous magnetic resonance (MR) imaging-guided laser ablation for the treatment of symptomatic soft tissue vascular malformations (VMs) in the face and neck.
An institutional review board-approved retrospective review was undertaken of all consecutive patients who underwent MR imaging-guided and monitored laser ablation for treatment of symptomatic, cervicofacial soft tissue VM. Preablation and postablation MR imaging findings were independently reviewed. Preablation and postablation VM sizes were documented. Preablation T2 signal characteristics and enhancement patterns as well as postablation change in both signal and enhancement were semiquantitatively assessed. Changes in VM size were compared using a paired t test.
Thirteen patients (women, 9; age, 14.5-69.5 years) with 13 VMs were treated for moderate-to-severe pain (n = 4), swelling/mass effect (n = 8), or predominantly cosmesis (n = 1) with 22 total ablation sessions. The baseline maximum VM diameter was 5.7 cm ± 4.2. At baseline, all VMs (100%) demonstrated variable T2-weighted signal hyperintensity and enhancement. For painful VM, the baseline pain score was 8 ± 1. Clinical follow-up was available for 10 patients. Of patients with available follow-up, 3 (100%) treated for moderate-to-severe pain and 7 (100%) treated for swelling/mass effect reported subjective complete or partial symptomatic relief. The patient treated predominantly for cosmetic reasons was lost to follow-up. Two patients (15.4%) experienced minor adverse events by the Society of Interventional Radiology standards. There were no major adverse events.
MR imaging-guided and monitored percutaneous laser ablation is safe and effective for the treatment of symptomatic, cervicofacial VMs.
评估经皮磁共振(MR)成像引导下激光消融治疗面颈部有症状的软组织血管畸形(VMs)的安全性和有效性。
对所有连续接受MR成像引导和监测下激光消融治疗有症状的颈面部软组织VM的患者进行了一项经机构审查委员会批准的回顾性研究。对消融前和消融后的MR成像结果进行独立评估。记录消融前和消融后VM的大小。对消融前T2信号特征和强化模式以及消融后信号和强化的变化进行半定量评估。使用配对t检验比较VM大小的变化。
13例患者(9例女性;年龄14.5 - 69.5岁)患有13处VM,因中度至重度疼痛(n = 4)、肿胀/肿块效应(n = 8)或主要为美容原因(n = 1)接受了总共22次消融治疗。基线时VM的最大直径为5.7 cm±4.2。基线时,所有VM(100%)均表现出不同程度的T2加权信号高强化。对于疼痛性VM,基线疼痛评分为8±1。10例患者有临床随访资料。在有随访资料的患者中,3例(100%)因中度至重度疼痛接受治疗,7例(100%)因肿胀/肿块效应接受治疗,均报告主观上完全或部分症状缓解。主要因美容原因接受治疗的患者失访。按照介入放射学会的标准,2例患者(15.4%)发生了轻微不良事件。无重大不良事件发生。
MR成像引导和监测下的经皮激光消融治疗有症状的颈面部VM是安全有效的。