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巴西圣卡塔琳娜州一家三级医院急诊科对深静脉血栓形成的诊断管理评估:一项横断面研究。

Evaluation of the diagnostic management of deep vein thrombosis in the emergency department of a tertiary hospital in Santa Catarina, Brazil: a cross-sectional study.

作者信息

Tramujas Lucas, Judice Márcio Mesquita, Becker Angela Bueno

机构信息

Hospital Governador Celso Ramos, Florianópolis, SC, Brasil.

Instituto de Pesquisa Hcor, São Paulo, SP, Brasil.

出版信息

J Vasc Bras. 2022 Oct 3;21:e20200217. doi: 10.1590/1677-5449.202002171. eCollection 2022.

Abstract

BACKGROUND

Venous thromboembolism is an entity that encompasses both deep vein thrombosis and pulmonary thromboembolism. Although protocols for the diagnosis of these diseases are well defined, there is evidence of inappropriate use of diagnostic resources.

OBJECTIVES

To define the epidemiological profiles of patients admitted to the emergency department with suspected deep vein thrombosis, to determine rates of inappropriate ordering of D-dimer assays and color venous Doppler echocardiography of the lower limbs, and to identify whether these requests followed the recommendations contained in the 2015 Brazilian Society of Angiology and Vascular Surgery guidelines.

METHODS

We conducted a cross-sectional observational study that retrospectively evaluated 168 patients with suspected deep vein thrombosis for whom D-dimer assays were requested. The most common risk factors were measured and the pretest probability was calculated with the Wells score. The epidemiological profile of these patients and the rates of inappropriate D-dimer testing were assessed using descriptive statistics.

RESULTS

The D-dimer requests were inadequate in 55 (32.7%) patients. Venous color Doppler ultrasound was used to examine the lower limbs of 14 (8.3%) of the patients with a low probability according to the Wells score and a negative D-dimer result. No additional diagnostic methods were used in 19 (11.3%) of those with a low probability according to the Wells score and a high D-dimer result. There was unnecessary use of CDUS in 35 (20.8%) cases. The overall rate of inappropriate workup was 53.5%.

CONCLUSIONS

Differences were found between clinical practice and the recommendations for diagnostic evaluation of patients with suspected deep vein thrombosis, with inappropriate use of diagnostic tests.

摘要

背景

静脉血栓栓塞症包括深静脉血栓形成和肺血栓栓塞。尽管这些疾病的诊断方案已明确,但仍有诊断资源使用不当的证据。

目的

确定因疑似深静脉血栓形成而入住急诊科患者的流行病学特征,确定D - 二聚体检测及下肢彩色静脉多普勒超声检查的不当开单率,并确定这些申请是否遵循了2015年巴西血管病学和血管外科学会指南中的建议。

方法

我们进行了一项横断面观察性研究,回顾性评估了168例申请D - 二聚体检测的疑似深静脉血栓形成患者。测量了最常见的危险因素,并使用Wells评分计算了检测前概率。使用描述性统计评估这些患者的流行病学特征和D - 二聚体检测不当的发生率。

结果

55例(32.7%)患者的D - 二聚体申请不恰当。根据Wells评分概率低且D - 二聚体结果为阴性的患者中有14例(8.3%)接受了下肢静脉彩色多普勒超声检查。根据Wells评分概率低且D - 二聚体结果高的患者中有19例(11.3%)未使用其他诊断方法。35例(20.8%)存在不必要的彩色多普勒超声检查。总体不恰当检查率为53.5%。

结论

在临床实践与疑似深静脉血栓形成患者诊断评估建议之间存在差异,存在诊断检查使用不当的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb39/9543468/2532c68ac416/jvb-21-e20200217-g01-en.jpg

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The epidemiology of venous thromboembolism.静脉血栓栓塞症的流行病学
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Appropriate use of D-dimer in hospital patients.在医院患者中适当使用 D-二聚体。
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