Gaghan Lindsey, Paci Karina, Foulke Galen, Googe Paul B, Lugo-Somolinos Aida
School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Dermatol Online J. 2022 Jun 15;28(3). doi: 10.5070/D328357783.
Lichen amyloidosis is believed to be caused by damage to keratinocytes, often by chronic scratching. It has also been associated with autoimmune conditions, including thyroid disease. Dermatologic manifestations of poorly controlled thyroid disease are well described within the medical literature, within both hypothyroid and hyperthyroid states. Myxedema is a rare complication of Graves disease. We report a unique case of concurrent myxedema and lichen amyloidosis in a 63-year-old patient with uncontrolled hypothyroidism in the setting of post-ablative Graves disease.
苔藓样淀粉样变被认为是由角质形成细胞受损引起的,通常是由于慢性搔抓。它还与自身免疫性疾病有关,包括甲状腺疾病。医学文献中对甲状腺疾病控制不佳的皮肤表现已有充分描述,包括甲状腺功能减退和甲状腺功能亢进状态。黏液性水肿是格雷夫斯病的一种罕见并发症。我们报告了一例63岁患有放射性碘治疗后格雷夫斯病且甲状腺功能减退控制不佳的患者,同时并发黏液性水肿和苔藓样淀粉样变的独特病例。