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孕期对COVID-19疫苗的接受情况

COVID-19 Vaccine Acceptance in Pregnancy.

作者信息

Odedokun Temitope, Marquez Rafael, Thakkar Meera, Dinglas Cheryl, Kady Dina El

机构信息

Department of Obstetrics and Gynecology/Maternal Fetal Medicine, Mount Sinai South Nassau, Oceanside, New York.

出版信息

Am J Perinatol. 2024 May;41(S 01):e617-e622. doi: 10.1055/s-0042-1757275. Epub 2022 Oct 19.

Abstract

OBJECTIVE

The purpose of the study is to evaluate the acceptance rate of the coronavirus disease 2019 (COVID-19) vaccine among pregnant women at our institution prior to recommendations by national organizations (American College of Obstetricians and Gynecologists/The Society for Maternal-Fetal Medicine) in July 2021 and to determine whether factors including health disparities are associated with acceptance.

STUDY DESIGN

This is an Institutional Review Board exempt descriptive study. Anonymous surveys were administered from February 2021 to May 2021 to pregnant patients at Mount Sinai South Nassau's affiliated Maternal Fetal Medicine office. The survey was completed by 701 pregnant women. Descriptive statistics were calculated for the overall sample, as well as separately by group (acceptance versus declining/undecided about getting the COVID-19 vaccine). The two groups were compared using the chi-square test or Fisher's exact test and the two-sample -test. Analysis was compared between two groups (patients who accepted the COVID-19 vaccine and people who declined/undecided about the vaccine). A result was considered statistically significant at the  < 0.05 level of significance.

RESULTS

Of the 701 pregnant women who completed the survey, 96 patients accepted the vaccine. More pregnant women who were older accepted the COVID-19 vaccine compared with those who were younger ( = 0.0343). Pregnant women willing to get the flu vaccine and/or the Tdap vaccine in pregnancy were more likely to obtain the COVID-19 vaccine ( < 0.05). Pregnant patients who had household members willing to receive the COVID-19 vaccine sought to obtain the vaccine for themselves ( < 0.0001). Interestingly, pregnant women who had an underlying respiratory illness in the pregnancy were less likely to accept the COVID-19 vaccine than those who had either other or no medical problems ( < 0.05).

CONCLUSION

There is a low rate of COVID-19 vaccine acceptance among pregnant women (13.69%). Efforts should be made to encourage the vaccine in this vulnerable population to protect them from the health risks of the COVID-19 virus.

KEY POINTS

· COVID-19 vaccine acceptance rates in our population were 13.6%.. · Accepting Tdap and influenza vaccines increased the likelihood of accepting the COVID vaccine.. · Pregnant patients with respiratory illnesses were more likely to decline the COVID vaccine..

摘要

目的

本研究旨在评估在2021年7月国家组织(美国妇产科医师学会/母胎医学协会)提出建议之前,我院孕妇对2019冠状病毒病(COVID-19)疫苗的接受率,并确定包括健康差异在内的因素是否与接受情况相关。

研究设计

这是一项经机构审查委员会豁免的描述性研究。2021年2月至2021年5月,对西奈山南拿骚附属母胎医学办公室的孕妇进行了匿名调查。701名孕妇完成了调查。对总体样本以及按组(接受与拒绝/未决定接种COVID-19疫苗)分别计算描述性统计数据。使用卡方检验或费舍尔精确检验以及两样本t检验对两组进行比较。对两组(接受COVID-19疫苗的患者和拒绝/未决定接种疫苗的人)进行分析比较。结果在显著性水平<0.05时被认为具有统计学意义。

结果

在完成调查的701名孕妇中,96名患者接受了疫苗。与年轻孕妇相比,年龄较大的孕妇接受COVID-19疫苗的更多(P = 0.0343)。愿意在孕期接种流感疫苗和/或破伤风、白喉、百日咳联合疫苗(Tdap)的孕妇更有可能接种COVID-19疫苗(P<0.05)。有家庭成员愿意接种COVID-19疫苗的孕妇自己也更倾向于接种该疫苗(P<0.0001)。有趣的是,孕期患有基础呼吸系统疾病的孕妇比那些有其他疾病或无疾病的孕妇更不太可能接受COVID-19疫苗(P<0.05)。

结论

孕妇中COVID-19疫苗的接受率较低(13.69%)。应努力鼓励这一弱势群体接种疫苗,以保护她们免受COVID-19病毒带来的健康风险。

要点

· 我们研究人群中COVID-19疫苗的接受率为13.6%。· 接受Tdap和流感疫苗会增加接受COVID疫苗的可能性。· 患有呼吸系统疾病的孕妇更有可能拒绝接种COVID疫苗。

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