Aoyama Takashi
Dietary Department, Shizuoka Cancer Center, Nagaizumicho, Shizuoka, Japan.
Nutr Metab Insights. 2022 Oct 14;15:11786388221129011. doi: 10.1177/11786388221129011. eCollection 2022.
We aimed to investigate the relationship between preoperative nutritional indicators and sarcopenia in patients diagnosed with stage III colorectal cancer for the first time. To this end, we evaluated the relationships of preoperative anthropometric and nutritional indices obtained by physical measurements and nutritional assessments with skeletal muscle mass index (SMI) measurements obtained using the bioelectrical impedance analysis (BIA) method. The participants were 135 patients (58 women; median age, 69 years). The anthropometric values obtained using an adipometer, and tape measure were evaluated in relation to the Japanese Anthropometric Reference Data (JARD 2001). The anthropometric values were associated with SMI and were highly sensitive to the sarcopenia reference cutoff values indicated by the Asian Working Group for Sarcopenia in 2019. Among the nutritional assessment tools, the Geriatric Nutritional Risk Index was associated with SMI. Thus, preoperative anthropometric values in stage III colorectal cancer patients were associated with measurements obtained using the BIA method and can be considered clinically significant.
我们旨在研究首次诊断为III期结直肠癌患者术前营养指标与肌肉减少症之间的关系。为此，我们评估了通过体格测量和营养评估获得的术前人体测量和营养指标与使用生物电阻抗分析（BIA）方法获得的骨骼肌质量指数（SMI）测量值之间的关系。参与者为135例患者（58名女性；中位年龄69岁）。使用脂肪测量仪和卷尺获得的人体测量值与日本人体测量参考数据（JARD 2001）相关进行评估。人体测量值与SMI相关，并且对2019年亚洲肌肉减少症工作组指出的肌肉减少症参考临界值高度敏感。在营养评估工具中，老年营养风险指数与SMI相关。因此，III期结直肠癌患者的术前人体测量值与使用BIA方法获得的测量值相关，可被认为具有临床意义。
