Timothy 综合征通往大脑的道路铺就于增强的 CaV1.2 激活门控。
The road to the brain in Timothy syndrome is paved with enhanced CaV1.2 activation gating.
机构信息
Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Canada.
出版信息
J Gen Physiol. 2022 Nov 7;154(11). doi: 10.1085/jgp.202213272. Epub 2022 Oct 20.
Abstract
Specific gating effects of Timothy syndrome Ca1.2 channel mutations determine cardiovascular versus nervous system deficits.
摘要
Timothy 综合征钙通道突变的特定门控效应决定了心血管与神经系统缺陷。
Zotero 插件