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儿童急性血源性骨髓炎:广泛骨质破坏的全骨干炎的治疗:13例儿童病例系列

Acute hematogenous osteomyelitis in children: Management of pandiaphysitis with extensive bone destruction: A case series of thirteen child.

作者信息

Zairi Mohamed, Mohseni Ahmed Amin, Msakni Ahmed, Jaber Chaker, Mensia Kacem, Saied Walid, Bouchoucha Sami, Boussetta Rim, Nessib Mohamed Nabil

机构信息

Faculty of Medicine of Tunis, Department of Pediatric Orthopedic Surgery, Bechir Hamza Children's Hospital, Tunis, Tunisia.

Faculty of Medicine of Tunis, Department of Cardiovascular Surgery, Hospital of Pneumo-Phtisiology Abderrahman Mami, Tunis, Tunisia.

出版信息

Ann Med Surg (Lond). 2022 Sep 8;82:104578. doi: 10.1016/j.amsu.2022.104578. eCollection 2022 Oct.

Abstract

INTRODUCTION

and Importance: Acute hematogenous osteomyelitis (AHO) poses a public health problem in severe forms from the outset or with delayed diagnosis. The aim of this work is to describe the management of pandiaphysitis with extensive bone destruction by the Ilizarov external fixator and antibiotics and to evaluate the results.

METHODS

This is a retrospective, descriptive, cross-sectional and single-center study. It was performed over a seven-year period. We included children with acute hematogenous osteomyelitis complicated by pandiaphysitis of the long bones with extensive bone necrosis. All patients underwent stabilization with an Ilizarov external fixator and antibiotic therapy adapted to the antibiogram in ten cases. One patient had the induced membrane technique. All the patients underwent dynamization of the Ilizarov external fixator followed by immobilization with a cast or a splint for the lower limb.

OUTCOMES

13 medical files were collected during the study period. The sex ratio was 1.6, the average age was 7.56 years. Three localization sites: humerus for 3 cases, femur for 3 cases and tibia for 7 cases. The germ has been identified in ten cases. Methicillin-resistant staphylococcus aureus was the most common. Bone consolidation is obtained in all cases with an average delay of ten months.

CONCLUSION

The Ilizarov external fixator associated with antibiotics has proven its effectiveness in the management of pandiaphysitis with extensive bone destruction. This method is an alternative in the therapeutic arsenal available to pediatric orthopedic surgeons.

LEVEL OF EVIDENCE

IV, Case series.

摘要

引言

及重要性:急性血源性骨髓炎(AHO)从一开始或诊断延迟时就会以严重形式构成公共卫生问题。本研究的目的是描述采用伊里扎洛夫外固定器和抗生素治疗广泛性骨破坏的全骨干骨髓炎的治疗方法并评估结果。

方法

这是一项回顾性、描述性、横断面单中心研究。研究历时七年。我们纳入了患有急性血源性骨髓炎并伴有长骨干广泛性骨坏死的全骨干骨髓炎患儿。所有患者均采用伊里扎洛夫外固定器进行固定,并根据药敏试验结果进行了十例抗生素治疗。一名患者采用了诱导膜技术。所有患者均对伊里扎洛夫外固定器进行了动力化处理,随后下肢采用石膏或夹板固定。

结果

研究期间收集了13份病历。男女比例为1.6,平均年龄为7.56岁。三个发病部位:肱骨3例,股骨3例,胫骨7例。十例患者明确了病原菌。耐甲氧西林金黄色葡萄球菌最为常见。所有病例均实现了骨愈合,平均延迟时间为十个月。

结论

伊里扎洛夫外固定器联合抗生素已证明其在治疗广泛性骨破坏的全骨干骨髓炎方面的有效性。该方法是小儿骨科医生可用治疗手段中的一种选择。

证据级别

IV,病例系列。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5018/9577533/ab25d6253a8f/gr1.jpg

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