Yadav Saroj Kumar, Bhattarai Himal Bikram, Rijal Ashes, Shrestha Anish, Shah Sangam, Subedi Ayusha, Yadav Binita Kumari, Acharya Aakash, Khatri Rojee, Kadel Gareema
Department of General Surgery, Koshi Hospital, Biratnagar, Nepal.
Gandaki Medical College, Pokhara, Nepal.
Ann Med Surg (Lond). 2022 Sep 8;82:104574. doi: 10.1016/j.amsu.2022.104574. eCollection 2022 Oct.
Gastrointestinal tumor (GIT) is an uncommon gastrointestinal tumor most commonly arising in the stomach. Duodenum is an uncommon site accounting for only about 3-5% of cases.
In this case report, we present a case of high-risk duodenal GIST and review its management strategies.
An abdominal mass and gastrointestinal (GI) bleeding are its usual presentation, however it may be lost among the long list of differentials of an abdominal mass and GI bleeding, if a high index of suspicion is not maintained. Surgery, with or without tyrosine kinase inhibitors like imatinib mesylate, has been the cornerstone in management of GIST.
This case underlined the importance of duodenal GIST as a cause of GI bleed and abdominal mass as well as shone light upon historical developments, current updates and managements of GISTs.
胃肠道肿瘤(GIT)是一种罕见的胃肠道肿瘤,最常发生于胃部。十二指肠是一个罕见的发病部位,仅占病例的约3 - 5%。
在本病例报告中,我们呈现了一例高危十二指肠胃肠道间质瘤(GIST)病例,并回顾其治疗策略。
腹部肿块和胃肠道(GI)出血是其常见表现,然而,如果没有保持高度的怀疑指数,它可能会在腹部肿块和GI出血的众多鉴别诊断中被遗漏。手术,无论是否联合使用如甲磺酸伊马替尼等酪氨酸激酶抑制剂,一直是GIST治疗的基石。
本病例强调了十二指肠GIST作为GI出血和腹部肿块病因的重要性,同时也揭示了GIST的历史发展、当前进展及治疗方法。