Lewis Cara C, Klasnja Predrag, Lyon Aaron R, Powell Byron J, Lengnick-Hall Rebecca, Buchanan Gretchen, Meza Rosemary D, Chan Michelle C, Boynton Marcella H, Weiner Bryan J
Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
School of Information, University of Michigan, Ann Arbor, MI, USA.
Implement Sci Commun. 2022 Oct 22;3(1):114. doi: 10.1186/s43058-022-00358-3.
There is a fundamental gap in understanding the causal mechanisms by which strategies for implementing evidence-based practices address local barriers to effective, appropriate service delivery. Until this gap is addressed, scientific knowledge and practical guidance about which implementation strategies to use in which contexts will remain elusive. This research project aims to identify plausible strategy-mechanism linkages, develop causal models for mechanism evaluation, produce measures needed to evaluate such linkages, and make these models, methods, and measures available in a user-friendly website. The specific aims are as follows: (1) build a database of strategy-mechanism linkages and associated causal pathway diagrams, (2) develop psychometrically strong, pragmatic measures of mechanisms, and (3) develop and disseminate a website of implementation mechanisms knowledge for use by diverse stakeholders.
For the first aim, a combination of qualitative inquiry, expert panel methods, and causal pathway diagramming will be used to identify and confirm plausible strategy-mechanism linkages and articulate moderators, preconditions, and proximal and distal outcomes associated with those linkages. For the second aim, rapid-cycle measure development and testing methods will be employed to create reliable, valid, pragmatic measures of six mechanisms of common strategies for which no high-quality measures exist. For the third aim, we will develop a user-friendly website and searchable database that incorporates user-centered design, disseminating the final product using social marketing principles.
Once strategy-mechanism linkages are identified using this multi-method approach, implementation scientists can use the searchable database to develop tailored implementation strategies and generate more robust evidence about which strategies work best in which contexts. Moreover, practitioners will be better able to select implementation strategies to address their specific implementation problems. New horizons in implementation strategy development, optimization, evaluation, and deployment are expected to be more attainable as a result of this research, which will lead to enhanced implementation of evidence-based interventions for cancer control, and ultimately improvements in patient outcomes.
在理解基于证据的实践策略解决有效、恰当服务提供的当地障碍的因果机制方面,存在一个基本差距。在这个差距得到解决之前,关于在何种背景下使用何种实施策略的科学知识和实践指导仍将难以捉摸。本研究项目旨在确定合理的策略 - 机制联系,开发用于机制评估的因果模型,生成评估此类联系所需的测量方法,并在一个用户友好的网站上提供这些模型、方法和测量方法。具体目标如下:(1)建立一个策略 - 机制联系及相关因果路径图的数据库,(2)开发心理测量学上强大且实用的机制测量方法,(3)开发并传播一个供不同利益相关者使用的实施机制知识网站。
对于第一个目标,将结合定性探究、专家小组方法和因果路径图绘制来识别和确认合理的策略 - 机制联系,并阐明与这些联系相关的调节因素、前提条件以及近端和远端结果。对于第二个目标,将采用快速循环测量开发和测试方法,为六种常见策略的机制创建可靠、有效且实用的测量方法,目前尚无针对这些策略的高质量测量方法。对于第三个目标,我们将开发一个用户友好的网站和可搜索数据库,采用以用户为中心的设计,并利用社会营销原则传播最终产品。
一旦使用这种多方法途径识别出策略 - 机制联系,实施科学家就可以使用可搜索数据库来制定量身定制的实施策略,并生成关于哪些策略在何种背景下效果最佳的更有力证据。此外,从业者将能够更好地选择实施策略来解决他们特定的实施问题。由于这项研究,实施策略开发、优化、评估和部署方面的新视野预计将更易于实现,这将导致加强基于证据的癌症控制干预措施的实施,并最终改善患者结局。