Digestive System Research Unit, University Hospital Vall d'Hebrón, Passeig de la Vall d'Hebron, 119, 08035 Barcelona, Spain; Autonomous University of Barcelona, Plaça Cívica, 08193 Bellaterra, Barcelona, Spain.
Digestive System Research Unit, University Hospital Vall d'Hebrón, Passeig de la Vall d'Hebron, 119, 08035 Barcelona, Spain; Autonomous University of Barcelona, Plaça Cívica, 08193 Bellaterra, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Av. Monforte de Lemos, 3-5, Pabellón 11, Planta 0, 28029 Madrid, Spain.
Gastroenterol Hepatol. 2023 Nov;46(9):663-670. doi: 10.1016/j.gastrohep.2022.10.014. Epub 2022 Oct 20.
BACKGROUND/AIMS: COVID-19 pandemic has produced an increased burden for motility laboratories due to the need to implement measures to minimize infection risk during examinations. International Societies have proposed algorithms for evaluation of active infection risk using symptom questionnaires or performing COVID-19 specific detection tests. The aim of the present study is to evaluate prospectively the independent value of a symptom-based questionnaire and RT-PCR test to detect COVID-19 infection before a digestive motility examination.
PATIENTS/METHODS: All patients referred for a motility study during a 4 month period with high incidence of COVID-19 in the community were prospectively evaluated with a symptom-questionnaire administered by phone one week before the examination, and a PCR test performed 48h before the examination, following international guidelines recommendations.
The symptom questionnaire could be obtained from 435 patients, 7 patients referred COVID-19 symptoms, but only 1 of them had a positive PCR. From 481 PCR tests performed, 8 were positive. Only 1 patient had reported symptoms in the previous questionnaire, and 2 additional patients developed COVID-19 symptoms later. Hence, 435 telephonic questionnaires should be done for one COVID-19 case detection (detection tax 0.22%); and 60 PCR should be performed for one COVID-19 case detection (detection tax 1.66%).
The use of screening strategies prior to a motility exploration results in a low rate of infection detection, especially the use of subjective symptom questionnaires, and the correct protection measures during motility explorations with aerosol generation remain the cornerstone to prevent COVID-19 infections.
背景/目的：由于在检查过程中需要实施措施以最大程度降低感染风险，COVID-19 大流行给运动实验室带来了更大的负担。国际社会已经提出了使用症状问卷或进行 COVID-19 特异性检测来评估活动性感染风险的算法。本研究的目的是前瞻性评估基于症状的问卷和 RT-PCR 检测在进行消化运动检查之前检测 COVID-19 感染的独立价值。
患者/方法：在社区 COVID-19 发病率较高的 4 个月期间，所有转介进行运动研究的患者均通过电话进行前瞻性评估，一周前进行症状问卷评估，48 小时前进行 PCR 检测，遵循国际指南建议。
可从 435 名患者中获得症状问卷，其中 7 名患者有 COVID-19 症状，但只有 1 名患者的 PCR 检测呈阳性。在进行的 481 次 PCR 检测中，有 8 次呈阳性。只有 1 名患者在之前的问卷中报告了症状，后来又有 2 名患者出现了 COVID-19 症状。因此，为了检测到 1 例 COVID-19，需要进行 435 次电话问卷（检测税 0.22%）；为了检测到 1 例 COVID-19，需要进行 60 次 PCR（检测税 1.66%）。
在进行运动探索之前使用筛查策略会导致感染检测率较低，尤其是使用主观症状问卷，并且在产生气溶胶的运动探索期间采取正确的保护措施仍然是预防 COVID-19 感染的基石。
