Ojemann L M, Baugh-Bookman C, Dudley D L
Neurology. 1987 Sep;37(9):1525-7. doi: 10.1212/wnl.37.9.1525.
Psychiatric problems are frequently encountered in patients with epilepsy. In an adult clinic population of 2,000 patients, 219 were identified as having been treated with psychotropic medication (PTM). Of these, 59 patients had adequate documentation of seizure frequency 2 months prior to and 2 months during treatment with PTMs. Contrary to many reports, most patients experienced better seizure control on PTM therapy. This demonstrates that most patients will not have an increased frequency of seizures when psychotropic medication is used in low to moderate doses and is introduced slowly.
癫痫患者经常会出现精神问题。在一个有2000名患者的成人门诊群体中，有219人被确定接受过精神药物治疗（PTM）。其中，59名患者有在接受精神药物治疗前2个月及治疗期间2个月的癫痫发作频率的充分记录。与许多报告相反，大多数患者在接受精神药物治疗时癫痫得到了更好的控制。这表明，当低至中等剂量使用精神药物并缓慢引入时，大多数患者的癫痫发作频率不会增加。
