Soni Kunal A, Bhende Vishal V, Sharma Tanishq S, Majmudar Hardil P, Kumar Amit, Trivedi Bhadra Y, Panesar Gurpreet, Dhami Kartik B, Tiwari Manish, Pathan Sohilkhan R
Cardiac Anesthesiology, Bhanubhai and Madhuben Patel Cardiac Centre, Shree Krishna Hospital, Bhaikaka University, Karamsad, IND.
Pediatric Cardiac Surgery, Bhanubhai and Madhuben Patel Cardiac Centre, Shree Krishna Hospital, Bhaikaka University, Karamsad, IND.
Cureus. 2022 Oct 19;14(10):e30479. doi: 10.7759/cureus.30479. eCollection 2022 Oct.
Preoperative exchange transfusion is frequently recommended in patients with homozygous sickle cell anemia (homozygous SS) who undergo cardiopulmonary bypass to reduce the concentration of circulated sickle hemoglobin. The information regarding the ideal level of sickle hemoglobin for sickle cell disease (SCD) patients who require surgery is still divergent in the literature. We present the successfully managed cases of two children aged 11 months and three years with homozygous SS who underwent cardiopulmonary bypass for double-outlet right ventricle and cor-triatriatum sinistrum, respectively. In both cases, we performed preoperative blood and exchange transfusion, as well as strict intraoperative invasive monitoring. We also maintained normothermia, avoided hypoxia and acidosis, and offered effective pain management.
对于接受体外循环的纯合子镰状细胞贫血（纯合子SS）患者，术前换血疗法常被推荐用于降低循环中镰状血红蛋白的浓度。关于需要手术的镰状细胞病（SCD）患者理想的镰状血红蛋白水平，文献中的信息仍存在分歧。我们介绍了两名分别为11个月和3岁的纯合子SS患儿的成功治疗病例，他们分别因右心室双出口和左房三房心接受了体外循环手术。在这两个病例中，我们都进行了术前血液和换血治疗，以及严格的术中侵入性监测。我们还维持了体温正常，避免了缺氧和酸中毒，并提供了有效的疼痛管理。
Zotero 插件