Yahiaoui Safia, Ghorbel Asma, Ben Zid Khadija, Zarraa Semia, Kchaou Lina, Kaabia Wael, Bouguerra Fadoua, Mousli Alia, Abidi Rim, Yousfi Amani, Nadia Boujelbene, Nasr Chiraz
Radiotherapy Department, Salah-Azaiz Institute, Bab Saadoun, Tunis, Tunisia.
Pathology Department, Salah-Azaiz Institute, Bab Saadoun, Tunis, Tunisia.
Rare Tumors. 2022 Oct 18;14:20363613221135987. doi: 10.1177/20363613221135987. eCollection 2022.
Langerhans histiocytosis or Langerhans cell histiocytosis (LCH) is a rare benign pathology representing less than 1% of orbital tumors. It can cause either localized or generalized lesions, leading to the destruction of hard and soft tissues. Eosinophilic granuloma is the most benign form and the predominant clinical presentation of LCH. We report a case of eosinophilic granuloma with orbital involvement in an 18-year-old male patient. Orbital radiotherapy was initially planned, but finally it was not performed due to a spontaneous regression of the lesion after the incisional biopsy. The presented case supports an expectant attitude given the possibility of a spontaneous regression after the biopsy, especially in small lesions. However, long-term follow-up is essential given the risk of recurrence.
朗格汉斯组织细胞增多症或朗格汉斯细胞组织细胞增多症（LCH）是一种罕见的良性病变，占眼眶肿瘤的比例不到1%。它可导致局部或全身性病变，进而破坏软硬组织。嗜酸性肉芽肿是LCH最良性的形式和主要临床表现。我们报告一例18岁男性患者发生眼眶受累的嗜酸性肉芽肿病例。最初计划进行眼眶放疗，但由于切开活检后病变自发消退，最终未实施放疗。鉴于活检后病变有自发消退的可能性，尤其是小病变，本病例支持采取观察等待的态度。然而，鉴于复发风险，长期随访至关重要。
