Manckoundia Patrick, Dipanda Mélanie, Mourey France
Pôle personnes âgées, centre hospitalier universitaire de Dijon, 2 rue Jules Violle, 21079 Dijon, France; Unité mixte de recherche Institut national de la santé et de la recherche médicale/U1093 Cognition, action et plasticité sensori-motrice, université de Bourgogne, 21078 Dijon Cedex, France.
Pôle personnes âgées, centre hospitalier universitaire de Dijon, 2 rue Jules Violle, 21079 Dijon, France.
Soins Gerontol. 2022 Sep-Oct;27(157):37-40. doi: 10.1016/j.sger.2022.09.008. Epub 2022 Sep 16.
For decades, the literature was skeptical about the feasibility of motor rehabilitation and its impact, as well as that of physical activity (PA), in subjects with major neurocognitive disorders (MNCD), including Alzheimer's disease. Now, authors report several benefits of PA, both physical and cognitive, by promoting brain perfusion, neurogenesis and synaptic plasticity, as well as decreasing oxidative stress and inflammation. PA should be recommended in cases of TNCM.
几十年来，文献一直对运动康复及其对包括阿尔茨海默病在内的重大神经认知障碍（MNCD）患者的影响以及体育活动（PA）的可行性持怀疑态度。现在，作者报告了体育活动在身体和认知方面的诸多益处，包括促进脑灌注、神经发生和突触可塑性，以及减少氧化应激和炎症。在重大神经认知障碍的情况下，应推荐进行体育活动。
