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一项评估客户对芬太尼检测试纸的理解和用于减少伤害的使用情况的试点研究。

A pilot study assessing client understanding and use of fentanyl test strips for harm reduction.

作者信息

Barrolle Aleeya A, Gable Kelly N, Dell Nathaniel

出版信息

J Am Pharm Assoc (2003). 2023 Jan-Feb;63(1):295-300. doi: 10.1016/j.japh.2022.09.018. Epub 2022 Sep 28.

Abstract

BACKGROUND

The Centers for Disease Control and Prevention reported a sharp increase in overdose deaths from illicitly manufactured fentanyls (IMFs) occurring between 2020 and 2021 in the United States. Approximately 4 in 10 drug overdose deaths involved opioids and stimulants. Fentanyl test strips (FTS), used to test drug product before use, can be a powerful harm reduction tool to promote safer use behaviors.

OBJECTIVES

This pilot study assessed treatment-seeking service users' knowledge and understanding of IMFs and motivation to use FTS to prevent overdose.

METHODS

Clients receiving residential-based or office-based substance use treatment services were recruited from a community mental health center in the midwestern United States to complete a harm reduction-focused survey. Eligibility criteria included clients aged 18-89 years with self-reported drug use in the past year. A 20-question survey was administered verbally, both in person and via phone to assess knowledge of IMFs and FTS.

RESULTS

Of respondents (N = 30), 80% agreed that IMFs cause more overdoses than heroin. Most (73%) indicated concern about a friend overdosing owing to IMFs, and half (53%) expressed concern about personal risk of overdose. Most (73%) would like to be able to detect whether there is fentanyl in their drug before use, but only 17% indicated that they feel confident in their ability to use FTS.

CONCLUSION

Many respondents who were receiving services for past-year substance use lacked understanding of how to use FTS for harm reduction. Clients who primarily use nonopioid (stimulant) drug products are at even greater risk of IMF overdose and would benefit the most from increased access and education surrounding the use of FTS. Our health care system must rapidly continue to explore and expand on overdose prevention efforts, including access to FTS, given that urgent action is needed to reduce the continued rise in overdose deaths in the United States.

摘要

背景

美国疾病控制与预防中心报告称,2020年至2021年间,美国非法制造的芬太尼(IMF)导致的过量用药死亡人数急剧增加。约十分之四的药物过量死亡涉及阿片类药物和兴奋剂。芬太尼检测试纸(FTS)用于在使用前检测药品,是促进更安全使用行为的有力减少伤害工具。

目的

这项试点研究评估了寻求治疗服务的使用者对IMF的了解以及使用FTS预防过量用药的动机。

方法

从美国中西部的一个社区心理健康中心招募接受住院或门诊物质使用治疗服务的客户,以完成一项以减少伤害为重点的调查。资格标准包括年龄在18 - 89岁、过去一年有自我报告吸毒行为的客户。通过面对面和电话方式进行了一项包含20个问题的口头调查,以评估对IMF和FTS的了解。

结果

在受访者(N = 30)中,80%同意IMF比海洛因导致更多过量用药情况。大多数(73%)表示担心朋友因IMF过量用药,一半(53%)表达了对个人过量用药风险的担忧。大多数(73%)希望能够在使用药物前检测其中是否含有芬太尼,但只有17%表示对自己使用FTS的能力有信心。

结论

许多过去一年接受物质使用服务的受访者不了解如何使用FTS来减少伤害。主要使用非阿片类(兴奋剂)药品的客户面临IMF过量用药的风险更高,增加FTS的获取和使用相关教育将使他们受益最大。鉴于需要采取紧急行动来减少美国过量用药死亡人数的持续上升,我们的医疗保健系统必须迅速继续探索和扩大过量用药预防工作,包括提供FTS。

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