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复杂性肾结石患者的尿路感染:与 Guy 结石评分有关吗?

Urinary tract infections in complicated kidney stones: Can they be correlated with Guy's stone score?

机构信息

Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania.

Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.

出版信息

J Pak Med Assoc. 2022 Sep;72(9):1721-1725. doi: 10.47391/JPMA.3172.

DOI:10.47391/JPMA.3172
PMID:36280963
Abstract

OBJECTIVE

To ascertain the existence of a connection between Guy's stone score and infectious complications after percutaneous nephrolitholapaxy.

METHODS

The retrospective cohort, multi-centre study was conducted in the urology departments of Prof Dr Theodor Burghele Clinical Hospital and C.I. Parhon Clinical Hospital, Romania, and included data of patients who underwent percutaneous nephrolitholapaxy from January 1, 2017, to December 31, 2019. Based on urography, the subjects were assigned to four groups, from GSS1 to GSS4, in accordance with the Guy's stone score classification. The complication rate after percutaneous nephrolitholapaxy was classified using the modified Clavien staging classification. Demographics, preoperative urine cultures, and the rate of complications were compared. Data was analysed using SPSS 24.

RESULTS

Of the 246 patients, 116(47.2%) were males and 130(52.8%) were females. The overall mean age was 53.06±13.04 years (range: 18-83). The mean Guy's stone score was 1.82±0.9. The rate of percutaneous nephrolitholapaxy success was 160(65.04%). There were 105(42.68%) patients in GSS1 group, 63(25.60%) in GSS2, 24(9.75%) in GSS3 and 54(21.95%) in GSS4. There were significantly more preoperative positive urine culture in GSS3 and GSS4 groups compared to GSS1 and GSS2 groups (p<0.05). The rates of complications were statistically different among the groups (p=0.019).

CONCLUSIONS

Urinary tract infections were found more frequently in patients with higher Guy's stone scores compared to those with low scores. The Guy's stone score classification were found to be a useful tool in predicting the immediate success rate of percutaneous nephrolitholapaxy.

摘要

目的

确定 Guy 结石评分与经皮肾镜碎石取石术后感染并发症之间是否存在关联。

方法

本回顾性队列多中心研究在罗马尼亚 Theodor Burghele 临床医院和 C.I. Parhon 临床医院的泌尿科进行,纳入了 2017 年 1 月 1 日至 2019 年 12 月 31 日期间接受经皮肾镜碎石取石术的患者数据。根据尿路造影,将受试者按照 Guy 结石评分分类分为 GSS1 至 GSS4 四组。经皮肾镜碎石取石术后并发症发生率采用改良 Clavien 分级分类。比较了人口统计学数据、术前尿液培养和并发症发生率。使用 SPSS 24 进行数据分析。

结果

在 246 名患者中,男性 116 名(47.2%),女性 130 名(52.8%)。总体平均年龄为 53.06±13.04 岁(范围:18-83 岁)。平均 Guy 结石评分为 1.82±0.9。经皮肾镜碎石取石术成功率为 160 名(65.04%)。GSS1 组有 105 名(42.68%)患者,GSS2 组有 63 名(25.60%),GSS3 组有 24 名(9.75%),GSS4 组有 54 名(21.95%)。与 GSS1 和 GSS2 组相比,GSS3 和 GSS4 组术前阳性尿液培养的患者明显更多(p<0.05)。各组之间的并发症发生率存在统计学差异(p=0.019)。

结论

与低评分患者相比,Guy 结石评分较高的患者更容易发生尿路感染。Guy 结石评分分类可作为预测经皮肾镜碎石取石术即刻成功率的有用工具。

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