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中国内镜医师行内镜下食管胃静脉曲张出血诊治报告。

Investigation report on endoscopic management of esophagogastric variceal bleeding by Chinese endoscopists.

机构信息

Digestive System Department, Capital Medical University Affiliated Beijing Shijitan Hospital, Beijing, China.

Endoscopy Center, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.

出版信息

Medicine (Baltimore). 2022 Oct 21;101(42):e31263. doi: 10.1097/MD.0000000000031263.

Abstract

BACKGROUND

Esophagogastric variceal bleeding (EGVB) is a potentially life-threatening complication of portal hypertension. Endoscopic treatment combined with pharmacotherapy remains the mainstay in the management of acute variceal bleeding.

AIM

This article intends to highlight the potential differences in the endoscopic management of EGVB in China.

METHODS

A cross-sectional descriptive study was conducted. Endoscopists from 85 hospitals in 62 cities from 26 provinces were contacted by email. The items in questionnaire involved academic experience, screening, esophagogastric varices (EGV) classification, emergency treatment, and primary and secondary prophylaxis of EGVB by endoscopists with different lengths of experience.

RESULTS

A total of 85 questionnaires were collected. There was no statistical difference in the selection of items (P < .05 indicated statistical significance). The majority of endoscopists (95.29%) offered EGV screening for patients with liver cirrhosis. The location, diameter, and risk factor classification was selected by 82.35% of endoscopists. Endoscopy + medication was preferred (42.35%) for the primary prophylaxis of moderate-to-severe EGVs. There was no statistical difference in emergency intervention time for active EGVB (P > .05). The response "patients receive emergency endoscopic intervention within 12 hours" was selected by 61.2% of the endoscopists. The preferred emergency treatment for EGVB was combination treatment (40%). Tissue adhesive embolization was selected for the treatment of gastric variceal bleeding by 74.12% of endoscopists; transjugular intrahepatic portosystemic stent shunt/percutaneous transhepatic variceal embolization were selected as remedial measures by 48.23% to 52.94% of endoscopists. In addition, 67.06% of endoscopists elected to perform secondary prophylaxis and treatment within 1 week after hemostasis. Endoscopy and endoscopy + medication were selected by 44.71% and 49.41% of endoscopists, respectively, for secondary prophylaxis. The choice of laboratory indicators did not differ with length of experience.

CONCLUSIONS

There was no statistical difference in the endoscopic management of EGVB among Chinese endoscopists. The selection of diagnosis/treatment schemes was mainly based on guidelines and physician experience.

摘要

背景

食管胃静脉曲张出血(EGVB)是门静脉高压的一种潜在危及生命的并发症。内镜治疗联合药物治疗仍然是急性静脉曲张出血管理的主要方法。

目的

本文旨在强调中国在 EGVB 内镜治疗方面的潜在差异。

方法

采用横断面描述性研究。通过电子邮件联系了来自中国 26 个省 62 个城市 85 家医院的内镜医生。问卷中的项目涉及内镜医生的学术经验、筛查、食管胃静脉曲张(EGV)分类、急症治疗以及 EGVB 的一级和二级预防。

结果

共收集了 85 份问卷。在项目选择方面无统计学差异(P<.05 表示具有统计学意义)。大多数内镜医生(95.29%)为肝硬化患者提供 EGV 筛查。82.35%的内镜医生选择 EGV 位置、直径和危险因素分类。内镜联合药物治疗(42.35%)被认为是预防中重度 EGV 的首选一级预防措施。活动性 EGVB 的急诊干预时间无统计学差异(P>.05)。61.2%的内镜医生选择“患者在 12 小时内接受紧急内镜干预”。EGVB 的首选急诊治疗方法是联合治疗(40%)。74.12%的内镜医生选择组织胶栓塞治疗胃静脉曲张出血;48.23%至 52.94%的内镜医生选择经颈静脉肝内门体分流术/经皮经肝静脉栓塞术作为补救措施。此外,67.06%的内镜医生选择在止血后 1 周内进行二级预防和治疗。44.71%和 49.41%的内镜医生分别选择内镜和内镜联合药物治疗进行二级预防。实验室指标的选择与经验无关。

结论

中国内镜医生在 EGVB 的内镜治疗方面没有统计学差异。诊断/治疗方案的选择主要基于指南和医生经验。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed73/9592513/5c3ca76ac702/medi-101-e31263-g001.jpg

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