Wang Guiqu, Liu Longqian
Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Department of Optometry and Visual Science, West China Hospital, Sichuan University, Chengdu, 610041, China.
Graefes Arch Clin Exp Ophthalmol. 2023 May;261(5):1229-1246. doi: 10.1007/s00417-022-05826-z. Epub 2022 Oct 25.
Amblyopia is a neurodevelopmental disorder characterized by functional deficits in the visual cortex. Functional magnetic resonance imaging (fMRI) is the most commonly used neuroimaging technique for investigating amblyopia. Herein, we systematically searched a PubMed database from inception to December 2021 to highlight the current progress and promises about fMRI technology in amblyopia; amblyopia's neural mechanism, the comparison of different types of amblyopia, and the evaluation of the therapeutic effect were explored. Relevant articles published in English and appropriate cross-references were considered for inclusion, including basic studies, imaging techniques, clinical diagnostic and therapeutic studies, case series, and reviews.
弱视是一种以视觉皮层功能缺陷为特征的神经发育障碍。功能磁共振成像(fMRI)是研究弱视最常用的神经成像技术。在此,我们系统检索了从创刊至2021年12月的PubMed数据库,以突出fMRI技术在弱视研究方面的当前进展和前景;探讨了弱视的神经机制、不同类型弱视的比较以及治疗效果评估。纳入考虑的是用英文发表的相关文章及适当的交叉参考文献,包括基础研究、成像技术、临床诊断与治疗研究、病例系列和综述。