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SFE-AFCE-SFMN 2022甲状腺结节管理共识:分子检测在甲状腺细针穿刺结果不确定结节中的作用

SFE-AFCE-SFMN 2022 Consensus on the management of thyroid nodules : Role of molecular tests for cytologically indeterminate thyroid nodules.

作者信息

Lasolle Hélène, Lopez Jonathan, Pattou François, Borson-Chazot Françoise, Bardet Stéphane, Groussin Lionel, Buffet Camille

机构信息

Fédération d'endocrinologie, Groupement Hospitalier Est, Hospices Civils de Lyon, Lyon, France; Inserm U1290, université Claude-Bernard Lyon 1, Lyon, France.

Département de biochimie et de biologie moléculaire, centre Hospitalier Lyon Sud, Hospices Civils de Lyon; Cancer Research Center of Lyon, Lyon 1 University, Lyon, France.

出版信息

Ann Endocrinol (Paris). 2022 Dec;83(6):395-400. doi: 10.1016/j.ando.2022.10.006. Epub 2022 Oct 23.

DOI:10.1016/j.ando.2022.10.006
PMID:36283464
Abstract

The SFE-AFCE-SFMN 2022 consensus deals with the management of thyroid nodules, a condition that is a frequent reason for consultation in endocrinology. In more than 90% of cases, patients are euthyroid, with benign non-progressive nodules that do not warrant specific treatment. The clinician's objective is to detect malignant thyroid nodules at risk of recurrence and death, toxic nodules responsible for hyperthyroidism or compressive nodules warranting treatment. The diagnosis and treatment of thyroid nodules requires close collaboration between endocrinologists, nuclear medicine physicians and surgeons, but also involves other specialists. Therefore, this consensus statement was established jointly by 3 societies: the French Society of Endocrinology (SFE), French Association of Endocrine Surgery (AFCE) and French Society of Nuclear Medicine (SFMN); the various working groups included experts from other specialties (pathologists, radiologists, pediatricians, biologists, etc.). Because of the emerging role of molecular fine-needle cytology diagnostics, the French Endocrine Society convened a panel of experts to review the evidence for the diagnostic value of molecular tests performed on cytologically indeterminate thyroid nodules.

摘要

《2022年法国内分泌学会-法国内分泌外科学会-法国核医学学会关于甲状腺结节管理的共识》探讨了甲状腺结节的管理问题,甲状腺结节是内分泌科常见的就诊原因。在超过90%的病例中,患者甲状腺功能正常,结节为良性且无进展,无需特殊治疗。临床医生的目标是检测出有复发和死亡风险的恶性甲状腺结节、导致甲状腺功能亢进的毒性结节或需要治疗的压迫性结节。甲状腺结节的诊断和治疗需要内分泌科医生、核医学医生和外科医生密切合作,但也涉及其他专科医生。因此,本共识声明由3个学会联合制定:法国内分泌学会(SFE)、法国内分泌外科学会(AFCE)和法国核医学学会(SFMN);各工作组包括来自其他专科(病理学家、放射科医生、儿科医生、生物学家等)的专家。由于分子细针细胞学诊断的作用日益凸显,法国内分泌学会召集了一个专家小组,以审查对甲状腺细针穿刺活检结果不确定的结节进行分子检测的诊断价值的证据。

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