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GeneXpert MTB/RIF 在结核病检测中的价值：基于文献计量学的分析与综述

The Value of GeneXpert MTB/RIF for Detection in Tuberculosis: A Bibliometrics-Based Analysis and Review.

作者信息

Li Zhiyi

机构信息

Laboratory Medicine, Nanan Hospital, Nanan, Quanzhou 362300, Fujian, China.

出版信息

J Anal Methods Chem. 2022 Oct 15;2022:2915018. doi: 10.1155/2022/2915018. eCollection 2022.

DOI:10.1155/2022/2915018
PMID:36284547
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9588380/
Abstract

With the continuous development of medical science and technology, especially with the advent of the era of precision diagnosis and treatment, molecular biology detection technology is widely valued and applied as an aid to early diagnosis of tuberculosis. The GeneXpert Branching (MTB) technology is a suite of semi-nested real-time fluorescent quantitative PCR in vitro diagnostic technologies developed by Cepheid Inc. It targets the rifampicin resistance gene, rpoB, and can detect both MTB and resistance to rifampicin within 2 h. This review analyzed the papers related to GeneXpert using bibliometric software CiteSpace and Bibliometrix. A total of 151 articles were analyzed, spanning from 2011 to 2021. This bibliometrics-based review summarizes the history of the development of GeneXpert in tuberculosis diagnosis and its current status. Contributions of different countries to the topic, journal analysis, key paper analysis, and clustering of keywords were used to analyze this topic.

摘要

随着医学科学技术的不断发展，尤其是精准诊断与治疗时代的到来，分子生物学检测技术作为结核病早期诊断的辅助手段受到广泛重视和应用。GeneXpert分枝杆菌（MTB）技术是赛沛公司开发的一套半巢式实时荧光定量PCR体外诊断技术。它以利福平耐药基因rpoB为靶点，可在2小时内检测出结核分枝杆菌及对利福平的耐药情况。本综述使用文献计量软件CiteSpace和Bibliometrix分析了与GeneXpert相关的论文。共分析了2011年至2021年期间的151篇文章。基于文献计量学的本综述总结了GeneXpert在结核病诊断中的发展历程及其现状。利用不同国家对该主题的贡献、期刊分析、关键论文分析以及关键词聚类对该主题进行了分析。

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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6856/9588380/79ace166cdec/JAMC2022-2915018.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6856/9588380/f052cbf1cc17/JAMC2022-2915018.007.jpg
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