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血液透析期间用于治疗透析中低血压和顽固性腹水的无细胞浓缩腹水回输疗法

Cell-Free and Concentrated Ascites Reinfusion Therapy during Hemodialysis for Intradialytic Hypotension and Intractable Ascites.

作者信息

Hayasaka Hideyuki, Ito Kiyonori, Ookawara Susumu, Kofuji Masaya, Uchida Takayuki, Kawamura Shunto, Gomyo Ayumi, Miyazawa Haruhisa, Ueda Yuichiro, Hirai Keiji, Kimura Shun-Ichi, Momose Naoki, Kako Shinichi, Morishita Yoshiyuki

机构信息

Department of Clinical Engineering, Saitama Medical Center, Jichi Medical University, Saitama, Japan.

Division of Nephrology, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan.

出版信息

Case Rep Nephrol. 2022 Oct 15;2022:7099227. doi: 10.1155/2022/7099227. eCollection 2022.

DOI:10.1155/2022/7099227
PMID:36284565
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9588379/
Abstract

A 60-year-old woman with POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) syndrome and intractable ascites presented with acute renal failure and received hemodialysis (HD) therapy. Due to frequent intradialytic hypotension, ultrafiltration with cell-free and concentrated ascites reinfusion therapy (CART) was performed to adequately manage the body fluid status and massive ascites. During HD with CART, her blood pressure was maintained compared with that during HD without CART, and an ultrafiltration volume of 3.7 L was achieved after HD with CART. In HD patients with intradialytic hypotension and massive ascites, the combination of CART and ultrafiltration during HD may be an effective therapeutic option for body-fluid management.

摘要

一名患有POEMS(多发性神经病、脏器肿大、内分泌病、单克隆丙种球蛋白病和皮肤改变)综合征且伴有顽固性腹水的60岁女性出现急性肾衰竭并接受了血液透析(HD)治疗。由于透析期间频繁发生低血压,遂采用无细胞浓缩腹水回输疗法(CART)进行超滤,以充分控制体液状态和大量腹水。在采用CART进行HD期间,与未采用CART进行HD时相比,她的血压得以维持,且采用CART进行HD后超滤量达到了3.7升。对于透析期间出现低血压和大量腹水的HD患者,HD期间CART与超滤相结合可能是控制体液的一种有效治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/178d/9588379/bbe01f01ee87/CRIN2022-7099227.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/178d/9588379/60a421c945c5/CRIN2022-7099227.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/178d/9588379/bbe01f01ee87/CRIN2022-7099227.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/178d/9588379/60a421c945c5/CRIN2022-7099227.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/178d/9588379/bbe01f01ee87/CRIN2022-7099227.002.jpg

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本文引用的文献

1
POEMS Syndrome: 2019 Update on diagnosis, risk-stratification, and management.POEMS 综合征:2019 年关于诊断、风险分层和管理的更新。
Am J Hematol. 2019 Jul;94(7):812-827. doi: 10.1002/ajh.25495. Epub 2019 May 23.
2
Dry weight targeting: The art and science of conventional hemodialysis.干体重目标设定:传统血液透析的技术与科学。
Semin Dial. 2018 Nov;31(6):551-556. doi: 10.1111/sdi.12721. Epub 2018 Jun 6.
3
Safety and efficacy of cell-free and concentrated ascites reinfusion therapy (CART) in refractory ascites: Post-marketing surveillance results.
无细胞浓缩腹水回输疗法(CART)治疗难治性腹水的安全性和有效性:上市后监测结果。
PLoS One. 2017 May 16;12(5):e0177303. doi: 10.1371/journal.pone.0177303. eCollection 2017.
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Cell-Free and Concentrated Ascites Reinfusion Therapy for Decompensated Liver Cirrhosis.无细胞浓缩腹水回输疗法治疗失代偿期肝硬化
Ther Apher Dial. 2016 Aug;20(4):376-82. doi: 10.1111/1744-9987.12469.
5
Cell-free and concentrated ascites reinfusion therapy (CART) for management of massive malignant ascites in gastric cancer patients with peritoneal metastasis treated with intravenous and intraperitoneal paclitaxel with oral S-1.采用静脉和腹腔注射紫杉醇联合口服S-1治疗的伴有腹膜转移的胃癌患者大量恶性腹水的无细胞浓缩腹水回输疗法(CART)
Eur J Surg Oncol. 2015 Jul;41(7):875-80. doi: 10.1016/j.ejso.2015.04.013. Epub 2015 May 8.
6
Albumin infusion for the critically ill--is it beneficial and, if so, why and how?重症患者输注白蛋白——有益吗?如果有益,原因和方式是什么?
Crit Care. 2015 Mar 30;19(1):156. doi: 10.1186/s13054-015-0862-4.
7
Effects of cell-free and concentrated ascites reinfusion therapy (CART) on symptom relief of malignancy-related ascites.无细胞腹水与浓缩腹水回输疗法(CART)对恶性肿瘤相关性腹水症状缓解的影响。
Int J Clin Oncol. 2015 Jun;20(3):623-8. doi: 10.1007/s10147-014-0750-y. Epub 2014 Sep 20.
8
Albumin administration in the acutely ill: what is new and where next?急性病患者白蛋白输注:有哪些新进展及后续方向?
Crit Care. 2014 Jul 16;18(4):231. doi: 10.1186/cc13991.
9
Japanese Society for Dialysis Therapy guidelines for management of cardiovascular diseases in patients on chronic hemodialysis.日本透析治疗学会慢性血液透析患者心血管疾病管理指南
Ther Apher Dial. 2012 Oct;16(5):387-435. doi: 10.1111/j.1744-9987.2012.01088.x.
10
Marked recovery of severe renal lesions in POEMS syndrome with high-dose melphalan therapy supported by autologous blood stem cell transplantation.大剂量美法仑治疗联合自体血干细胞移植支持下,POEMS综合征严重肾脏病变显著恢复。
Am J Kidney Dis. 2006 Apr;47(4):672-9. doi: 10.1053/j.ajkd.2006.01.004.