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经对侧大脑半球间经大脑镰入路治疗楔前叶胶质母细胞瘤:荧光素引导下的显微手术切除及内镜显微检查工具

Contralateral interhemispheric transfalcine approach to precuneal glioblastoma: fluorescein guided microsurgical resection and endoscopic microinspection tool.

作者信息

Olszewski Adam M, Tranmer Bruce I, Liebelt Brandon D

机构信息

Department of Neurosurgery, University of Vermont Medical Center, Burlington, Vermont.

出版信息

Neurosurg Focus Video. 2022 Jan 1;6(1):V11. doi: 10.3171/2021.10.FOCVID21195. eCollection 2022 Jan.

DOI:10.3171/2021.10.FOCVID21195
PMID:36284580
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9557337/
Abstract

Maximum safe resection remains a primary goal in the treatment of glioblastoma, with gross-total resection conveying additional survival benefit. Multiple intraoperative visualization techniques have been developed to improve the extent of resection. Herein, the authors describe the use of fluorescein and endoscopic assistance with a novel microinspection device in achieving a gross-total resection of a deep seated precuneal glioblastoma. An interhemispheric transfalcine approach was utilized and microsurgical resection was completed with fluorescein guidance. A 45° endoscope was then used to inspect the resection bed, and remaining areas of concern were then resected under endoscopic visualization. The video can be found here: https://stream.cadmore.media/r10.3171/2021.10.FOCVID21195.

摘要

最大安全切除仍然是胶质母细胞瘤治疗的主要目标,全切除可带来额外的生存益处。已开发出多种术中可视化技术以提高切除范围。在此,作者描述了使用荧光素和一种新型显微检查设备辅助内镜,实现对深部楔前叶胶质母细胞瘤的全切除。采用经胼胝体间经大脑镰入路,并在荧光素引导下完成显微手术切除。然后使用45°内镜检查切除腔,随后在内镜直视下切除其余可疑区域。视频可在此处查看:https://stream.cadmore.media/r10.3171/2021.10.FOCVID21195 。

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本文引用的文献

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Contralateral Interhemispheric Transfalcine Approach for Intra-Axial Medial Occipital Lesion: 2-Dimensional Operative Video.经对侧大脑半球间经大脑镰入路治疗枕叶内侧轴内病变:二维手术视频
Oper Neurosurg. 2019 Nov 1;17(5):E208-E209. doi: 10.1093/ons/opz016.
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Fluorescein Guidance in Glioblastoma Resection.胶质母细胞瘤切除术中的荧光素引导
N Engl J Med. 2017 May 4;376(18):e36. doi: 10.1056/NEJMicm1611258.
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Gross Total Resection of Glioblastoma Improves Overall Survival and Progression-Free Survival Compared to Subtotal Resection or Biopsy Alone.
与仅行次全切除或活检相比,胶质母细胞瘤的全切除可改善总生存期和无进展生存期。
Neurosurgery. 2016 Dec;79(6):N12-N13. doi: 10.1227/01.neu.0000508600.08200.c1.
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Association of the Extent of Resection With Survival in Glioblastoma: A Systematic Review and Meta-analysis.胶质母细胞瘤切除范围与生存的相关性:一项系统评价和荟萃分析。
JAMA Oncol. 2016 Nov 1;2(11):1460-1469. doi: 10.1001/jamaoncol.2016.1373.
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Neurosurgical oncology: advances in operative technologies and adjuncts.神经外科肿瘤学:手术技术与辅助手段的进展
J Neurooncol. 2014 Sep;119(3):451-63. doi: 10.1007/s11060-014-1493-3. Epub 2014 Jun 27.
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Neuro-oncologic applications of endoscopy.内镜在神经肿瘤学中的应用。
Neurosurg Clin N Am. 2004 Jan;15(1):89-103. doi: 10.1016/S1042-3680(03)00068-8.
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Current surgical management of glioblastoma.胶质母细胞瘤的当前外科治疗方法
Cancer J. 2003 Mar-Apr;9(2):113-25. doi: 10.1097/00130404-200303000-00007.