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三叉神经束间神经松解术(神经梳理术)治疗多发性硬化症中的难治性复发性神经痛

Trigeminal interfascicular neurolysis (nerve combing) for refractory recurrent neuralgia in multiple sclerosis.

作者信息

Ferroli Paolo, Vetrano Ignazio G, Acerbi Francesco, Raccuia Gabriella, Schiariti Marco, Confalonieri Paolo, Chiapparini Luisa, Broggi Morgan

机构信息

Neurosurgical Unit II, Department of Neurosurgery.

Unit of Neuroimmunology and Neuromuscular Diseases, and.

出版信息

Neurosurg Focus Video. 2020 Oct 1;3(2):V3. doi: 10.3171/2020.5.FOCVID203. eCollection 2020 Oct.

DOI:10.3171/2020.5.FOCVID203
PMID:36285264
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9542691/
Abstract

In multiple sclerosis (MS) patients, trigeminal neuralgia (TN) represents a challenging syndrome to treat, often refractory to medical therapy and percutaneous techniques. Despite the frequent lack of a neurovascular conflict, the trigeminal nerve's axons are often damaged, with the myelin sheath permanently degenerated, thus explaining the difficulty in treating TN in MS. The authors illustrate trigeminal interfascicular neurolysis (the combing technique) to control refractory recurrent TN in MS: the nerve is longitudinally divided along its fibers from the root entry zone, determining good pain relief. The video can be found here: https://youtu.be/o1XksPW5fMY.

摘要

在多发性硬化症(MS)患者中,三叉神经痛(TN)是一种难以治疗的综合征,通常对药物治疗和经皮技术无效。尽管经常不存在神经血管冲突,但三叉神经的轴突经常受损,髓鞘永久退化,这就解释了MS中TN治疗的困难。作者阐述了三叉神经束间神经松解术(梳理技术)来控制MS中难治性复发性TN:从神经根入区沿神经纤维纵向分开神经,可有效缓解疼痛。视频链接如下:https://youtu.be/o1XksPW5fMY 。

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引用本文的文献

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本文引用的文献

1
Trigeminal neuralgia in multiple sclerosis: Prevalence and association with demyelination.多发性硬化症中的三叉神经痛:患病率及与脱髓鞘的关系。
Acta Neurol Scand. 2020 Aug;142(2):139-144. doi: 10.1111/ane.13243. Epub 2020 Apr 3.
2
Nerve Combing for Trigeminal Neuralgia Without Vascular Compression.无血管压迫性三叉神经痛的神经梳理术
J Craniofac Surg. 2017 Jan;28(1):e15-e16. doi: 10.1097/SCS.0000000000003161.
3
Options in treating trigeminal neuralgia: Experience with 195 patients.三叉神经痛的治疗选择:195例患者的经验
Clin Neurol Neurosurg. 2016 Oct;149:166-70. doi: 10.1016/j.clineuro.2016.08.016. Epub 2016 Aug 17.
4
Trigeminal neuralgia without evidence of neurovascular conflict: microvascular compression or route entry zone exploration?无神经血管冲突证据的三叉神经痛:微血管减压术还是入路区探查?
World Neurosurg. 2013 Sep-Oct;80(3-4):300-1. doi: 10.1016/j.wneu.2012.10.042. Epub 2012 Oct 24.
5
Surgical technique for trigeminal microvascular decompression.三叉神经微血管减压术的手术技术。
Acta Neurochir (Wien). 2012 Jun;154(6):1089-95. doi: 10.1007/s00701-012-1324-2. Epub 2012 Apr 25.
6
Operative findings in cases of trigeminal neuralgia without vascular compression: proposal of a different mechanism.无血管压迫的三叉神经痛病例的手术发现:一种不同机制的提议
J Clin Neurosci. 2002 Mar;9(2):200-4. doi: 10.1054/jocn.2001.0922.