Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, USA.
J Bacteriol. 2022 Nov 15;204(11):e0038622. doi: 10.1128/jb.00386-22. Epub 2022 Oct 26.
In the , a highly adhesive polysaccharide called the holdfast mediates attachment to exogenous surfaces. The mechanism by which this polysaccharide is anchored to the cell envelope is not well defined. N. K. Chepkwony, G. G. Hardy, and Y. V. Brun (J Bacteriol 204:e00273-22, 2022, https://doi.org/10.1128/jb.00273-22) report the characterization of HfaE, a localized surface protein with amyloid-like properties that is required for robust holdfast anchoring. This study expands our understanding of the protein factors that attach a bacterial "superglue" to the surface of the cell.
在这篇论文中，一种名为附着胞的高粘性多糖介导了对外源表面的附着。然而，这种多糖与细胞包膜结合的机制尚不清楚。N. K. Chepkwony、G. G. Hardy 和 Y. V. Brun（J Bacteriol 204:e00273-22, 2022, https://doi.org/10.1128/jb.00273-22）报道了 HfaE 的特征，HfaE 是一种具有淀粉样特性的局部表面蛋白，是牢固附着胞附着所必需的。这项研究扩展了我们对将细菌“超级胶水”附着到细胞表面的蛋白质因素的理解。
