[急性淋巴细胞白血病患者嵌合抗原受体T细胞疗法相关细胞因子释放综合征的体外细胞因子清除。病例报告]
[Extracorporeal cytokine removal in chimeric antigen receptor T-cell therapy associated cytokine release syndrome in patient with acute lymphoblastic leukemia. Case report].
作者信息
Shchekina A E, Galstyan G M, Gavrilina O A, Arapova N M, Bronyakina S I, Kotova E S, Troitskaya V V, Parovichnikova E N, Maschan M A, Savchenko V G
机构信息
National Research Center for Hematology.
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology.
出版信息
Ter Arkh. 2021 Jul 23;93(7):811-817. doi: 10.26442/00403660.2021.07.200931.
Сytokine release syndrome is the common complication of CAR-T therapy. We report a case of patient with B-cell acute lymphoblastic leukemia developing сytokine release syndrome with shock and multiple organ failure and requiring cytokine removal and hemodiafiltration. Remission of the disease was achieved after CAR-T therapy.
细胞因子释放综合征是嵌合抗原受体T细胞（CAR-T）疗法的常见并发症。我们报告了1例B细胞急性淋巴细胞白血病患者发生伴有休克和多器官功能衰竭的细胞因子释放综合征，需要进行细胞因子清除和血液透析滤过治疗。该患者在接受CAR-T治疗后病情缓解。
Zotero 插件