Galstyan G M, Maschan A A, Klebanova E E, Kalinina I I
National Research Center for Hematology.
Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology.
Ter Arkh. 2021 Jul 23;93(7):826-829. doi: 10.26442/00403660.2021.07.200914.
The review discusses approaches to treatment of congenital thrombotic thrombocytopenic purpura (TTP) or Upshaw-Schulman syndrome. In congenital TTP, plasma transfusions are sufficient. Such treatment options as plasma exchange, administration of clotting factor VIII concentrate, recombinant ADAMTS13, are also used. Separately discussed issues of management of patients with TTP during pregnancy, and pediatric patients with TTP.
这篇综述讨论了先天性血栓性血小板减少性紫癜（TTP）或乌-舒综合征的治疗方法。对于先天性TTP，输血治疗就足够了。也会使用诸如血浆置换、输注凝血因子VIII浓缩物、重组ADAMTS13等治疗方案。另外还讨论了TTP患者在孕期的管理问题以及儿童TTP患者的管理问题。
