Terenicheva M A, Stukalova O V, Shakhnovich R M, Ternovoy S K
Myasnikov Institute of Clinical Cardiology, National Medical Research Center of Cardiology.
Sechenov First Moscow State Medical University (Sechenov University).
Ter Arkh. 2022 May 26;94(4):552-557. doi: 10.26442/00403660.2022.04.201458.
Currently the incidence of congestive heart failure after ST-segment elevation myocardial infarction (STEMI) tends to increase. Reperfusion therapy is still the only effective method to reduce an infarct size. Therefore, there is a high unmet need of novel cardioprotective treatments that would improve outcomes in such patients. Recent advances in cardiovascular magnetic resonance (CMR) methods enabled the identification of certain new infarct characteristics associated with the development of heart failure and sudden cardiac death. These characteristics can help identify new groups of high risk patients and used as a targets for novel cardioprotective treatments. This part of the review summarizes novel CMR-based characteristics of myocardial infarction and their role in the prognostic stratification of STEMI patients.
目前，ST段抬高型心肌梗死（STEMI）后充血性心力衰竭的发病率呈上升趋势。再灌注治疗仍然是缩小梗死面积的唯一有效方法。因此，对于能够改善此类患者预后的新型心脏保护治疗存在着尚未满足的高度需求。心血管磁共振（CMR）方法的最新进展使得能够识别与心力衰竭和心源性猝死发生相关的某些新的梗死特征。这些特征有助于识别新的高危患者群体，并作为新型心脏保护治疗的靶点。本综述的这一部分总结了基于CMR的心肌梗死新特征及其在STEMI患者预后分层中的作用。
