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偏头痛与头痛学会(德国偏头痛与头痛协会、奥地利头痛协会和瑞士头痛协会)关于偏头痛药物预防性治疗疗程的共识声明

[Consensus statement of the migraine and headache societies (DMKG, ÖKSG, and SKG) on the duration of pharmacological migraine prophylaxis].

作者信息

Goßrau Gudrun, Förderreuther Stefanie, Ruscheweyh Ruth, Ruschil Victoria, Sprenger Till, Lewis David, Kamm Katharina, Freilinger Tobias, Neeb Lars, Malzacher Volker, Meier Uwe, Gehring Klaus, Kraya Torsten, Dresler Thomas, Schankin Christoph J, Gantenbein Andreas R, Brössner Gregor, Zebenholzer Karin, Diener Hans-Christoph, Gaul Charly, Jürgens Tim P

机构信息

Kopfschmerzambulanz, Universitätsschmerzcentrum, Medizinische Fakultät der TU Dresden, Universitätsklinikum Dresden, Fetscherstr. 74, 01307, Dresden, Deutschland.

Neurologische Klinik und Poliklinik, Ludwig-Maximilians-Universität München, München, Deutschland.

出版信息

Nervenarzt. 2023 Apr;94(4):306-317. doi: 10.1007/s00115-022-01403-1. Epub 2022 Oct 26.

DOI:10.1007/s00115-022-01403-1
PMID:36287216
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9607745/
Abstract

Migraine is the most common neurological disorder and can be associated with a high degree of disability. In addition to non-pharmacological approaches to reduce migraine frequency, pharmacological migraine preventatives are available. Evidence-based guidelines from the German Migraine and Headache Society (DMKG), and German Society for Neurology (DGN), Austrian Headache Society (ÖKSG), and Swiss Headache Society (SKG) are available for indication and application. For therapy-relevant questions such as the duration of a pharmacological migraine prevention, no conclusions can be drawn from currently available study data. The aim of this review is to present a therapy consensus statement that integrates the current data situation and, where data are lacking, expert opinions. The resulting current recommendations on the duration of therapy for pharmacological migraine prophylaxis are shown here.

摘要

偏头痛是最常见的神经系统疾病,可能导致高度残疾。除了采用非药物方法来降低偏头痛发作频率外,也有偏头痛的药物预防性治疗方法。德国偏头痛与头痛协会(DMKG)、德国神经病学学会(DGN)、奥地利头痛协会(ÖKSG)和瑞士头痛协会(SKG)发布了关于适应证和应用的循证指南。对于诸如药物性偏头痛预防疗程等与治疗相关的问题,目前可得的研究数据无法得出结论。本综述的目的是提出一份治疗共识声明,该声明整合了当前的数据情况,并在缺乏数据时纳入专家意见。以下展示了由此得出的关于药物性偏头痛预防治疗疗程的当前建议。

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Model-Informed Approach Supporting Drug Development and Regulatory Evaluation for Rare Diseases.模型指导方法支持罕见病的药物开发和监管评估。
J Clin Pharmacol. 2022 Dec;62 Suppl 2:S27-S37. doi: 10.1002/jcph.2143.
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Three Dimensions of Association Link Migraine Symptoms and Functional Connectivity.偏头痛症状与功能连接的三个关联维度。
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European Headache Federation guideline on the use of monoclonal antibodies targeting the calcitonin gene related peptide pathway for migraine prevention - 2022 update.欧洲头痛联合会关于使用靶向降钙素基因相关肽通路的单克隆抗体预防偏头痛的指南-2022 更新版。
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The association between onabotulinumtoxinA and anti-CGRP monoclonal antibodies: a reliable option for the optimal treatment of chronic migraine.肉毒杆菌毒素 A 与抗 CGRP 单克隆抗体的关联:慢性偏头痛最佳治疗的可靠选择。
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Resumption of migraine preventive treatment with CGRP(-receptor) antibodies after a 3-month drug holiday: a real-world experience.在停药3个月后恢复使用降钙素基因相关肽(CGRP)(受体)抗体进行偏头痛预防性治疗:一项真实世界的经验。
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Real-world assessment of the relationship between migraine-related disability and healthcare costs in the United States.真实世界评估美国偏头痛相关残疾与医疗保健费用之间的关系。
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