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用于超高分辨率成像的混合 CT 系统的在线几何校准。

Online Geometric Calibration of a Hybrid CT System for Ultrahigh-Resolution Imaging.

机构信息

Biochemistry and Biophysics Center, Laboratory of Imaging Physics, National Heart, Lung and Blood Institute, Division of Intramural Research, National Institutes of Health, Bethesda, MD 20892, USA.

Cardiovascular CT, Cardiovascular Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

出版信息

Tomography. 2022 Oct 12;8(5):2547-2555. doi: 10.3390/tomography8050212.

Abstract

A hybrid imaging system consisting of a standard computed tomography (CT) scanner and a low-profile photon-counting detector insert in contact with the patient's body has been used to produce ultrahigh-resolution images in a limited volume in chest scans of patients. The detector insert is placed on the patient bed as needed and not attached. Thus, its position and orientation in the scanner is dependent on the patient's position and scan settings. To allow accurate image reconstruction, we devised a method of determining the relative geometry of the detector insert and the CT scanner for each scan using fiducial markers. This method uses an iterative registration algorithm to align the markers in the reconstructed volume from the detector insert to that of the concurrent CT scan. After obtaining precise geometric information of the detector insert relative to the CT scanner, the two complementary sets of images are summed together to create a detailed image with reduced artifacts.

摘要

一种混合成像系统,由一个标准的计算机断层扫描(CT)扫描仪和一个与患者身体接触的低轮廓光子计数探测器插入件组成,已被用于在患者胸部扫描中有限体积内产生超高分辨率图像。探测器插入件根据需要放置在患者床上,不固定。因此,其在扫描仪中的位置和方向取决于患者的位置和扫描设置。为了允许准确的图像重建,我们设计了一种使用基准标记确定探测器插入件和 CT 扫描仪在每次扫描中的相对几何形状的方法。该方法使用迭代配准算法将来自探测器插入件的重建体积中的标记与同期 CT 扫描中的标记对齐。在获得探测器插入件相对于 CT 扫描仪的精确几何信息后,将这两组互补的图像相加在一起,创建一个具有减少伪影的详细图像。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adce/9610615/ae85ce365709/tomography-08-00212-g001.jpg

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