Sibrecht Greta, Wróblewska-Seniuk Katarzyna, Kornacki Jakub, Boroń Daniel, Szydłowski Jarosław, Kłosowska Anna, Bień Ewa, Wender-Ożegowska Ewa, Szczapa Tomasz
II Department of Neonatology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
Department of Reproduction, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
Biomedicines. 2022 Sep 28;10(10):2422. doi: 10.3390/biomedicines10102422.
Masses of the head and neck are often diagnosed prenatally and require special care due to the risk of airway obstruction. The EXIT procedure is a preferable mode of delivery. A congenital cystic lymphatic malformation is one of the most common lesions of the cervical region described in neonates. The treatment consists of different strategies and involves the cooperation of multiple specialists. Up to now, no guidelines or protocols are available. We report a case of a congenital cystic lymphatic malformation of the head and neck delivered during the EXIT procedure by a mother who was SARS-CoV-2 positive. We analyzed clinical characteristics, radiologic features, and treatment with injections of sclerotic agents and orally administrated sirolimus. Sirolimus seems a valuable and safe therapeutic option for treating lymphatic malformations, especially with adjunct therapies.
头颈部肿块常在产前被诊断出来，由于存在气道梗阻风险，需要特殊护理。产时宫外治疗（EXIT）手术是一种较好的分娩方式。先天性囊状淋巴管瘤是新生儿颈部最常见的病变之一。治疗包括不同策略，需要多个专科医生协作。到目前为止，尚无指南或方案。我们报告一例头颈部先天性囊状淋巴管瘤病例，患儿母亲为新冠病毒阳性，通过EXIT手术分娩。我们分析了临床特征、影像学特征以及硬化剂注射和口服西罗莫司的治疗情况。西罗莫司似乎是治疗淋巴管瘤的一种有价值且安全的治疗选择，尤其是联合其他治疗方法时。
