Sartelli Massimo, Cristini Francesco, Coccolini Federico, Labricciosa Francesco Maria, Siquini Walter, Catena Fausto
Department of Surgery, Macerata Hospital, 62100 Macerata, Italy.
Infectious Disease Department, Rimini Hospital, 47926 Rimini, Italy.
Antibiotics (Basel). 2022 Oct 12;11(10):1394. doi: 10.3390/antibiotics11101394.
Adequately controlling the source of infection and prescribing appropriately antibiotic therapy are the cornerstones of the management of patients with intra-abdominal infections (IAIs). Correctly classifying patients with IAIs is crucial to assessing the severity of their clinical condition and deciding the strategy of the treatment, including a correct empiric antibiotic therapy. Best practices in prescribing antibiotics may impact patient outcomes and the cost of treatment, as well as the risk of "opportunistic" infections such as infection and the development and spread of antimicrobial resistance. This review aims to identify a correct classification of IAIs, guiding clinicians in the selection of the best antibiotic therapy in patients with IAIs.
充分控制感染源并合理使用抗生素治疗是腹腔内感染(IAIs)患者管理的基石。正确对IAIs患者进行分类对于评估其临床病情严重程度以及决定治疗策略(包括正确的经验性抗生素治疗)至关重要。抗生素处方的最佳实践可能会影响患者的治疗结果、治疗成本以及诸如感染等“机会性”感染的风险,还有抗菌药物耐药性的产生和传播。本综述旨在确定IAIs的正确分类,指导临床医生为IAIs患者选择最佳抗生素治疗。