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关于指导腹腔内感染合适抗生素治疗选择的分类建议

A Proposal for a Classification Guiding the Selection of Appropriate Antibiotic Therapy for Intra-Abdominal Infections.

作者信息

Sartelli Massimo, Cristini Francesco, Coccolini Federico, Labricciosa Francesco Maria, Siquini Walter, Catena Fausto

机构信息

Department of Surgery, Macerata Hospital, 62100 Macerata, Italy.

Infectious Disease Department, Rimini Hospital, 47926 Rimini, Italy.

出版信息

Antibiotics (Basel). 2022 Oct 12;11(10):1394. doi: 10.3390/antibiotics11101394.

DOI:10.3390/antibiotics11101394
PMID:36290052
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9598485/
Abstract

Adequately controlling the source of infection and prescribing appropriately antibiotic therapy are the cornerstones of the management of patients with intra-abdominal infections (IAIs). Correctly classifying patients with IAIs is crucial to assessing the severity of their clinical condition and deciding the strategy of the treatment, including a correct empiric antibiotic therapy. Best practices in prescribing antibiotics may impact patient outcomes and the cost of treatment, as well as the risk of "opportunistic" infections such as infection and the development and spread of antimicrobial resistance. This review aims to identify a correct classification of IAIs, guiding clinicians in the selection of the best antibiotic therapy in patients with IAIs.

摘要

充分控制感染源并合理使用抗生素治疗是腹腔内感染(IAIs)患者管理的基石。正确对IAIs患者进行分类对于评估其临床病情严重程度以及决定治疗策略(包括正确的经验性抗生素治疗)至关重要。抗生素处方的最佳实践可能会影响患者的治疗结果、治疗成本以及诸如感染等“机会性”感染的风险,还有抗菌药物耐药性的产生和传播。本综述旨在确定IAIs的正确分类,指导临床医生为IAIs患者选择最佳抗生素治疗。

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本文引用的文献

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Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021.拯救脓毒症运动:2021年脓毒症和脓毒性休克国际管理指南
Intensive Care Med. 2021 Nov;47(11):1181-1247. doi: 10.1007/s00134-021-06506-y. Epub 2021 Oct 2.
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WSES/GAIS/SIS-E/WSIS/AAST global clinical pathways for patients with intra-abdominal infections.WSES/GAIS/SIS-E/WSIS/AAST 全球腹腔内感染患者临床路径。
World J Emerg Surg. 2021 Sep 25;16(1):49. doi: 10.1186/s13017-021-00387-8.
3
Acute abdomen in the immunocompromised patient: WSES, SIS-E, WSIS, AAST, and GAIS guidelines.免疫功能低下患者的急腹症:WSES、SIS-E、WSIS、AAST 和 GAIS 指南。
World J Emerg Surg. 2021 Aug 9;16(1):40. doi: 10.1186/s13017-021-00380-1.
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An Evidence-Based Multidisciplinary Approach Focused at Creating Algorithms for Targeted Therapy of BSIs, cUTIs, and cIAIs Caused by in Critically Ill Adult Patients.一种基于证据的多学科方法,专注于为重症成年患者中由[病原体名称未给出]引起的血流感染、复杂性尿路感染和复杂性腹腔内感染创建靶向治疗算法。
Infect Drug Resist. 2021 Jun 30;14:2461-2498. doi: 10.2147/IDR.S314241. eCollection 2021.
5
CON: Testing for ESBL production is unnecessary for ceftriaxone-resistant Enterobacterales.反对观点:对于对头孢曲松耐药的肠杆菌科细菌,检测超广谱β-内酰胺酶的产生没有必要。
JAC Antimicrob Resist. 2021 May 7;3(2):dlab020. doi: 10.1093/jacamr/dlab020. eCollection 2021 Jun.
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Infectious Diseases Society of America Guidance on the Treatment of Extended-Spectrum β-lactamase Producing Enterobacterales (ESBL-E), Carbapenem-Resistant Enterobacterales (CRE), and Pseudomonas aeruginosa with Difficult-to-Treat Resistance (DTR-P. aeruginosa).美国传染病学会关于产超广谱β-内酰胺酶肠杆菌科(ESBL-E)、耐碳青霉烯肠杆菌科(CRE)和治疗困难的耐药铜绿假单胞菌(DTR-P. aeruginosa)的治疗指南。
Clin Infect Dis. 2021 Apr 8;72(7):e169-e183. doi: 10.1093/cid/ciaa1478.