Belzer Annika, Weiss Emma, Etaee Farshid, Bunick Christopher G, Damsky William, Nelson Caroline A
Yale School of Medicine, New Haven, CT 06510, USA.
Department of Dermatology, Yale School of Medicine, New Haven, CT 06510, USA.
Antibiotics (Basel). 2022 Oct 12;11(10):1398. doi: 10.3390/antibiotics11101398.
is a Gram-negative bacillus that causes skin and soft tissue infections (SSTI), as well as bacteremia, pneumonia, and urinary tract infections. infections are typically nosocomial and are often transmitted through water sources. Although historically described in immunocompromised hosts, prevalence is increasing in both immunocompromised and immunocompetent populations. In light of high morbidity and mortality, it is critical that dermatologists are aware of this organism because of the limited options for therapy. Here, we describe a case of a abscess with bacteremia in a patient with chronic lymphocytic leukemia and aplastic anemia that was successfully treated with trimethoprim-sulfamethoxazole. We also review the current standard of care and propose an algorithm for the treatment of infection.
是一种革兰氏阴性杆菌,可引起皮肤和软组织感染(SSTI),以及菌血症、肺炎和尿路感染。感染通常为医院获得性,常通过水源传播。尽管历史上多在免疫功能低下的宿主中描述,但在免疫功能低下和免疫功能正常人群中的患病率均在增加。鉴于其高发病率和死亡率,皮肤科医生了解这种病原体至关重要,因为治疗选择有限。在此,我们描述了一例慢性淋巴细胞白血病和再生障碍性贫血患者发生的伴有菌血症的脓肿病例,该病例用甲氧苄啶-磺胺甲恶唑成功治疗。我们还回顾了当前的护理标准,并提出了一种治疗感染的算法。