Epidemiology of Species at a Tertiary Hospital in Southern Taiwan, 2012 to 2020: MLSA Phylogeny and Antimicrobial Susceptibility.

The identification and antimicrobial susceptibility of spp. are essential for guiding antibiotic treatment. We investigated the species distribution and evaluated the antimicrobial susceptibility of species collected in southern Taiwan from 2012 to 2020. A total of 77 isolates were collected and identified to the species level using multi-locus sequence analysis (MLSA). The susceptibilities to 15 antibiotics for isolates were determined by the broth microdilution method, and the MIC and MIC for each antibiotic against different species were analyzed. was the leading isolate, accounting for 32.5% of all isolates, and the prevalence of isolates decreased in summer. All of the isolates were susceptible to trimethoprim/sulfamethoxazole, amikacin, and linezolid, whereas 90.9% were non-susceptible to cefepime and imipenem. The phylogenic tree by MLSA showed that the similarity between and was as high as 99%, 73% between and , and 86% between and . While trimethoprim/sulfamethoxazole, amikacin, and linezolid remained fully active against all of the isolates tested, 90.9% of the isolates were non-susceptible to cefepime and imipenem.