Ben Hamida M, Hentati F, Ben Hamida C
Rev Neurol (Paris). 1987;143(4):284-9.
The case of a 15 year-old girl, who had difficulties in walking from early childhood is reported. The clinical picture was that of the rigid spine syndrome, spine rigidity being associated with retractions and diffuse amyotrophy of the upper limbs. Histochemical and ultra-structural studies of the muscle showed typical multiminicores. The multiminicore myopathy has not particular clinical features. In the rigid spine syndrome various histological changes can be found. For these reasons, we think that the rigid spine syndrome should be classified within the group of congenital myopathies.
报告了一名15岁女孩的病例，该女孩自幼行走困难。临床表现为僵硬脊柱综合征，脊柱僵硬伴有上肢回缩和弥漫性肌萎缩。肌肉的组织化学和超微结构研究显示典型的多微小核。多微小核肌病没有特殊的临床特征。在僵硬脊柱综合征中可发现各种组织学变化。基于这些原因，我们认为僵硬脊柱综合征应归类于先天性肌病组。
