Department of Student Affairs, Baylor College of Medicine, Houston, TX 77030, USA.
Department of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Curr Oncol. 2022 Sep 28;29(10):7051-7058. doi: 10.3390/curroncol29100553.
: We describe our experience with the development of hepatobiliary infection in patients with prior surgical, percutaneous, or endoscopic biliary interventions who are receiving transarterial radioembolization (TARE) with yttrium-90 (Y) for primary or metastatic hepatobiliary lesions. : Records of 15 patients with a history of prior biliary intervention and liver malignancy subsequently treated with TARE at the participating medical center from November 2009 to September 2015 were reviewed. The primary endpoint was the development of a hepatic abscess or cholangitis in a patient after radioembolization. : A total of 15 patients comprising 9 men and 6 women, with a median age of 49 years (range 30-73), underwent 17 TARE with Y procedures. Of the 15 patients, 2 (13.3%) of them developed a hepatobiliary infection. A single patient (6.6%) developed a hepatobiliary abscess. : Our study shows a low incidence rate of hepatic abscess following TARE in patients with prior biliary intervention.
我们描述了我们在接受钇-90(Y)经动脉放射栓塞(TARE)治疗原发性或转移性肝胆肿瘤的患者中,既往有外科、经皮或内镜胆道介入治疗史的患者发生肝胆感染的经验。
回顾了 2009 年 11 月至 2015 年 9 月期间在参与医疗中心接受 TARE 治疗的 15 例既往有胆道干预和肝恶性肿瘤病史的患者的记录。主要终点是放射栓塞后患者发生肝脓肿或胆管炎。
15 例患者包括 9 名男性和 6 名女性,中位年龄为 49 岁(范围 30-73),共进行了 17 次 Y 经 TARE 治疗。在 15 例患者中,2 例(13.3%)发生了肝胆感染。1 例患者(6.6%)发生了肝胆脓肿。
我们的研究表明,既往有胆道干预的患者接受 TARE 后肝脓肿的发生率较低。