Liang Pengpeng, Li Yufei, Feng Yanan, Yin Guoliang, Chen Suwen, Liu Xiangyi, Zhang Fengxia
The First Clinical Medical College, Qianfoshan Campus, Shandong University of Traditional Chinese Medicine, 16369 Jingshi Rd., Jinan 250000, China.
Department of Neurology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, 16369 Jingshi Rd., Jinan 250011, China.
Brain Sci. 2022 Sep 23;12(10):1282. doi: 10.3390/brainsci12101282.
The purpose of this study was to evaluate the rehabilitation effects of four common interventions (BA: body acupuncture, SA: scalp acupuncture, TA: tongue acupuncture, SLT: speech and language training) used singly or in combination with language function in patients with post-stroke aphasia (PSA).
We systematically searched PubMed, EMBASE, Cochrane Library, Ovid, Web of Science, CNKI, VIP, and Wanfang from inception to 4 April 2022. Only randomized controlled trials that met the eligibility criteria were included. The risk of bias of studies included was assessed using the RoB-2 tool. The effects of different interventions for PSA patients were analyzed and ranked according to the surface under the cumulative ranking (SUCRA) analysis.
A total of 69 RCTs were included, including 5097 total participants. According to the results of the SUCRA curves, TA ranked highest in improving overall efficacy (SUCRA = 86%) and oral expression score (SUCRA = 86%). BA + TA ranked highest in increasing the comprehension score (SUCRA = 74.9%). BA + SA ranked highest in improving aphasia patients' repetition (SUCRA = 89.2%) and denomination scores (SUCRA = 93%).
Results of our network meta-analysis and SUCRA ranking showed that tongue acupuncture, body acupuncture + tongue acupuncture, and body acupuncture + scalp acupuncture seem to offer better advantages than other interventions for improving the language function in PSA patients. Moreover, it is noteworthy that our results are limited to the Chinese population, since all eligible studies are from China. Future well-designed studies with larger sample sizes and more ethnic groups are required to further verify these findings.
本研究旨在评估四种常见干预措施（体针、头针、舌针、言语语言训练）单独或联合使用对脑卒中后失语症（PSA）患者语言功能的康复效果。
我们系统检索了从数据库建库至2022年4月4日的PubMed、EMBASE、Cochrane图书馆、Ovid、Web of Science、中国知网、维普和万方数据库。仅纳入符合纳入标准的随机对照试验。使用RoB-2工具评估纳入研究的偏倚风险。根据累积排序曲线下面积（SUCRA）分析对PSA患者不同干预措施的效果进行分析和排序。
共纳入69项随机对照试验，总计5097名参与者。根据SUCRA曲线结果，舌针在提高总体疗效（SUCRA = 86%）和口语表达得分（SUCRA = 86%）方面排名最高。体针 + 舌针在提高理解得分方面排名最高（SUCRA = 74.9%）。体针 + 头针在改善失语症患者的复述（SUCRA = 89.2%）和命名得分方面排名最高（SUCRA = 93%）。
我们的网状Meta分析和SUCRA排序结果表明，舌针、体针 + 舌针以及体针 + 头针在改善PSA患者语言功能方面似乎比其他干预措施具有更好的优势。此外，值得注意的是，我们的结果仅限于中国人群，因为所有符合条件的研究均来自中国。未来需要设计更完善、样本量更大且涉及更多种族群体的研究来进一步验证这些发现。
