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卵胞浆内单精子注射后双绒毛膜三胎妊娠合并联体双胎:1例病例报告及文献复习

Conjoined Twins Complicating a Dichorionic Triplet Pregnancy after Intracytoplasmic Sperm Injection: A Case Report and Review of the Literature.

作者信息

Eleftheriades Anna, Christopoulos Panagiotis, Tsapakis Elsa, Tsarna Ermioni, Vlahos Nikolaos F, Kalampokas Emmanouil, Bolla Daniele, Eleftheriades Makarios

机构信息

Postgraduate Programme "Fetal Maternal Medicine'', Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.

Department of Obstetrics and Gynaecology, Hospital of Langenthal-Region Oberaargau, 4900 Langenthal, Switzerland.

出版信息

Children (Basel). 2022 Oct 12;9(10):1549. doi: 10.3390/children9101549.

DOI:10.3390/children9101549
PMID:36291485
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9600585/
Abstract

Conjoined twins represent a rare type of monoamniotic twins. Ultrasound assessment during the first trimester can facilitate the diagnosis, however further assessment by colour Doppler studies, 3D imaging, fetal echocardiography and fetal magnetic resonance imaging (MRI) is usually required in order to determine the specific fetal abnormalities and to guide appropriate pregnancy management. This case report presents a rare case of conjoined twins complicating a dichorionic-diamniotic triplet pregnancy, achieved after intracytoplasmic sperm injection (ICSI) and blastocyst transfer. A 44-year-old woman was referred for chorionicity determination to our Fetal Medicine Centre due to suspicion of conjoined twins in a triplet pregnancy. Ultrasound assessment at 11 weeks demonstrated a dichorionic triplet pregnancy which was also complicated by a rare type of conjoined twins (thoracoomphalopagus) and after a successful embryo reduction a neonate of 2200 g was delivered by caesarean section at term. The accurate diagnosis and early detection of conjoined twins by a fetal medicine specialist is crucial, especially as far as multiple pregnancies with three or more fetuses are concerned.

摘要

联体双胎是单羊膜囊双胎的一种罕见类型。孕早期的超声评估有助于诊断,但通常还需要通过彩色多普勒检查、三维成像、胎儿超声心动图和胎儿磁共振成像(MRI)进行进一步评估,以确定具体的胎儿异常情况并指导适当的孕期管理。本病例报告呈现了一例罕见的联体双胎合并双绒毛膜双羊膜囊三胎妊娠的病例,该妊娠是通过胞浆内单精子注射(ICSI)和囊胚移植实现的。一名44岁女性因三胎妊娠疑似联体双胎被转诊至我们的胎儿医学中心进行绒毛膜性判定。孕11周时的超声评估显示为双绒毛膜三胎妊娠,同时还合并一种罕见类型的联体双胎(胸腹联体双胎),成功减胎后,足月时通过剖宫产分娩出一名体重2200克的新生儿。胎儿医学专家对联体双胎的准确诊断和早期检测至关重要,尤其是对于三胎或更多胎儿的多胎妊娠而言。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c3e/9600585/1e3dd804994c/children-09-01549-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c3e/9600585/c791ec6743fb/children-09-01549-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c3e/9600585/d929fd550d2e/children-09-01549-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c3e/9600585/1dc987c62b6e/children-09-01549-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c3e/9600585/1e3dd804994c/children-09-01549-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c3e/9600585/c791ec6743fb/children-09-01549-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c3e/9600585/d929fd550d2e/children-09-01549-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c3e/9600585/1dc987c62b6e/children-09-01549-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c3e/9600585/1e3dd804994c/children-09-01549-g004.jpg

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Births: Final Data for 2020.出生人数:2020 年最终数据。
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Conjoined twins in dichorionic diamniotic triplet pregnancy: a report of three cases and literature review.三绒毛膜三羊膜性妊娠中的联体双胎:三例报告及文献复习。
BMC Pregnancy Childbirth. 2021 Oct 8;21(1):687. doi: 10.1186/s12884-021-04165-x.
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First-trimester diagnosis of conjoined twins in a multifetal pregnancy after assisted reproduction technique using HDlive rendering.在辅助生殖技术后多胎妊娠中使用高清实时渲染技术进行孕早期联体双胎诊断。
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Triplet pregnancy from the transfer of two blastocysts demonstrating a twin reversed arterial perfusion sequence with a conjoined-twins pump fetus.两枚囊胚移植后发生三胎妊娠,其中出现双胎反向动脉灌注序列,并伴有联体双胎泵血胎儿。
Int J Gynaecol Obstet. 2017 May;137(2):196-197. doi: 10.1002/ijgo.12123. Epub 2017 Mar 7.
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Conjoined twins in a monochorionic triplet pregnancy after in vitro fertilization: a case report.体外受精后单绒毛膜三胎妊娠中的联体双胎:一例报告
Iran J Reprod Med. 2015 Nov;13(11):729-32.
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Conjoined twins in a triplet pregnancy: a case report.三胎妊娠中的联体双胎:一例报告
Case Rep Obstet Gynecol. 2011;2011:235873. doi: 10.1155/2011/235873. Epub 2011 Sep 6.
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Conjoined hearts in thoracopagus twins.胸腹联体双胎中的联体心脏。
Pediatr Cardiol. 2012 Feb;33(2):252-7. doi: 10.1007/s00246-011-0125-3. Epub 2011 Sep 30.
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Conjoined twins: a worldwide collaborative epidemiological study of the International Clearinghouse for Birth Defects Surveillance and Research.联体双胞胎:国际出生缺陷监测和研究信息交换中心的一项全球性协作流行病学研究。
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