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以孤立性硬膜外肿块为表现的原发性恶性淋巴瘤

Primary Malignant Lymphoma Presenting as an Isolated Epidural Mass.

作者信息

Kim Haksung, Kim Daekyun, Kim Seokwon

机构信息

Department of Neurosurgery, College of Medicine, Chosun University, Gwangju 61453, Korea.

出版信息

Diagnostics (Basel). 2022 Oct 11;12(10):2462. doi: 10.3390/diagnostics12102462.

Abstract

Primary central nervous system lymphoma is a rare form of extranodal non-Hodgkin's lymphoma that occurs in the brain, spinal cord, leptomeninges, or eyes and typically remains confined to the central nervous system. Among them, malignant lymphoma presenting as a primary tumor of the spinal cord is extremely uncommon, and epidural mass formation is known to occur in only 0.8-2.8% of cases of malignant lymphomas. Furthermore, primary malignant lymphoma presenting as an isolated epidural mass is much rarer. Here, we report a case of primary malignant lymphoma of the thoracic spine presenting as an isolated epidural mass that did not involve the vertebral body or posterior element. Surgical decompression is essential to prevent further neurological deterioration. Here, we present a successful treatment strategy for this rare case.

摘要

原发性中枢神经系统淋巴瘤是一种罕见的结外非霍奇金淋巴瘤,发生于脑、脊髓、软脑膜或眼睛,通常局限于中枢神经系统。其中,表现为脊髓原发性肿瘤的恶性淋巴瘤极为罕见,已知硬膜外肿块形成仅发生在0.8%-2.8%的恶性淋巴瘤病例中。此外,表现为孤立性硬膜外肿块的原发性恶性淋巴瘤更为罕见。在此,我们报告一例胸椎原发性恶性淋巴瘤,表现为孤立性硬膜外肿块,未累及椎体或后部结构。手术减压对于防止神经功能进一步恶化至关重要。在此,我们介绍了针对这一罕见病例的成功治疗策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e933/9600437/835911c32078/diagnostics-12-02462-g001.jpg

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