Ștefan Mihai, Predoi Cornelia, Goicea Raluca, Filipescu Daniela
Department of Anaesthesiology and Intensive Care, "Prof Dr CC Iliescu" Emergency Institute for Cardiovascular Diseases, 022322 Bucharest, Romania.
Discipline of Anaesthesiology and Intensive Care, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
J Clin Med. 2022 Oct 13;11(20):6031. doi: 10.3390/jcm11206031.
Recent research has contested the previously accepted paradigm that volatile anaesthetics improve outcomes in cardiac surgery patients when compared to intravenous anaesthesia. In this review we summarise the mechanisms of myocardial ischaemia/reperfusion injury and cardioprotection in cardiac surgery. In addition, we make a comprehensive analysis of evidence comparing outcomes in patients undergoing cardiac surgery under volatile or intravenous anaesthesia, in terms of mortality and morbidity (cardiac, neurological, renal, pulmonary).
最近的研究对先前被接受的范式提出了质疑,该范式认为与静脉麻醉相比,挥发性麻醉剂可改善心脏手术患者的预后。在本综述中,我们总结了心脏手术中心肌缺血/再灌注损伤和心脏保护的机制。此外,我们还对在挥发性或静脉麻醉下接受心脏手术的患者在死亡率和发病率(心脏、神经、肾脏、肺部)方面的预后比较证据进行了全面分析。